1279712-23-0Relevant articles and documents
Application of oxone immobilized on montmorillonite for an efficient oxidation of mannose thioglycoside
Polakova, Monika,Jankovic, Lubos,Kuckova, Lenka,Kozisek, Jozef
, p. 969 - 973 (2013)
A new solid system based on montmorillonite supported oxone has been developed and used for the oxidation of thiomannoside. The oxidation properties of oxone immobilized on montmorillonite were affected by polarity of the solvent, resulting in the different sulfoxide to sulfone ratios as the products. Toluene was the only solvent favouring sulfone formation over sulfoxide. X-ray crystal structures of the starting compound as well as the corresponding sulfoxide (major epimer Rs) and sulfone are also reported. Graphical Abstract: [Figure not available: see fulltext.]
α-d-Mannose derivatives as models designed for selective inhibition of Golgi α-mannosidase II
Poláková, Monika,?esták, Sergej,Lattová, Erika,Petru?, Ladislav,Mucha, Ján,Tvaro?ka, Igor,Kóňa, Juraj
experimental part, p. 944 - 952 (2011/04/12)
Human Golgi α-mannosidase II (hGM) is a pharmaceutical target for the design of inhibitors with anti-tumor activity. Nanomolar inhibitors of hGM exhibit unwanted co-inhibition of the human lysosomal α-mannosidase (hLM). Hence, improving specificity of the