128-42-7Relevant academic research and scientific papers
Stilbene type compound as well as synthesis method and application thereof
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Paragraph 0008; 0041; 0052; 0063, (2021/07/01)
The invention discloses a stilbene type compound as well as a synthesis method and application thereof, wherein the synthesis method comprises the steps: taking an intermediate 2 and an intermediate 4 as initiators, sequentially carrying out Wittig reaction, reduction reaction, amino protection reaction, condensation reaction, deprotection reaction and amidation reaction, and then refining to obtain the stilbene type compound. The synthesis process is high in controllability, used reagents are low in price, and the method is simple and easy to industrialize. The stilbene type compound can be used as a medicine for resisting tumors and viruses and treating fungal infection and cardiovascular and cerebrovascular diseases.
DSD acid preparation method
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, (2017/11/03)
The invention relates to the field of chemical synthesis, in particular to a DSD acid preparation method. The DSD acid preparation method includes the steps that methylbenzene is subjected to sulfonation, purification and separation to obtain OTS, wherein the byproduct is PTS; OTS is subjected to mixed acid nitration to obtain PNTS; PNTS is subjected to chlorine oxidative condensation to obtain DNS; DNS is subjected to catalyzed hydrogeneration reduction to obtain the high-quality target product, namely DSD acid which can be directly used for synthesizing a fluorescent whitening agent. The synthesis method greatly reduces dangerousness of the process, greatly reduces generation of harmful byproducts and waste, particularly, does not generate a lot of carcinogenic intermediate, namely ortho-nitrotoluene, completely solves the nitration safety problem of the old technology, and has the advantages of being simple in step, high in yield and the like.
Dehydrogenation of nitro derivatives of bibenzyl to corresponding nitro stilbene with dioxygen catalyzed by 2,2,6,6-tetramethylpiperidine-1-oxyl
Lu, Tingting,Lu, Ming
, p. 971 - 975 (2013/02/25)
A simple and effective oxidative dehydrogenation of nitro derivatives of bibenzyl was developed using a mixture of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and metal salts as catalyst under an atmospheric pressure of oxygen. The oxidation of several nitro derivatives of bibenzyl led to corresponding nitro stilbene in good yields, and the yields increased with the increase in the substituted nitro group on the bibenzyl. For example, the aerobic dehydrogenation of 2,2,4,4,6,6-hexanitrobibenzyl in the presence of a catalytic amount of TEMPO with metal salts gave 2,2,4,4,6,6-hexanitrostilbene in 81 % yield and 4,4-dinitrostilbene-2,2-disulfonic acid (75 %) was obtained from 4,4-dinitrobibenzyl-2,2-disulfonic acid. Iranian Chemical Society 2012.
[1]BENZOTHIENO[3,2-B][1]BENZOTHIOPHENE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME
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Page/Page column 36, (2009/12/02)
A [1]benzothieno[3,2-b][1]benzothiophene compound expressed by General Formula (I): General Formula (I) where X and Y are each independently a hydrogen atom; a halogen atom; or a functional group having a straight or branched aliphatic alkyl group optionally having a halogen atom, a functional group having an alicyclic alkyl group optionally having a halogen atom, a functional group having a straight or branched aliphatic alkenyl group optionally having a halogen atom, a functional group having an alicyclic alkenyl group optionally having a halogen atom, a functional group having a carboxyl group, or a functional group having a thiol group, as a partial structure; and X and Y are the same or each independently different, provided that at least one of X and Y has a straight or branched aliphatic alkenyl group, an alicyclic alkenyl group, a carboxyl group or a thiol group, as a partial structure.
PANEL-HEATING UNIT FOR COMBINED HEATING
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, (2007/11/03)
The panel-heating unit (1) for combined heating that is equipped in the corners of at least one of its heating panels (2) with the fittings (3,4,5,6) for heating medium and which is alternatively equipped on its side with a compact valve garniture (7) together with the lower body (8), this one consisting of together firmly interconnected lower main return flow outlet fitting (3) and the onward flow inlet fitting (9) with the attached delivery pipe (10), which flows out into upper fitting (5), when this piece is typically equipped with regulation elements (11) to control the flow of heating medium, and the said heating unit is equipped in the way that its lower main fitting (3) and the lower secondary return flow fitting (4) located on the external side of the panel-heating unit (1) are together firmly interconnected to allow for medium circulation and the major section of the interconnection of the said fittings consists of the hollow profile (12) which is positioned parallel to the lower edge of the panel-heating unit (1) and the said profile is designed to be equipped with an electrical heater (13).
Modified methods for the synthesis of triazinyl fluorescent brightener intermediates
Safaei-Ghomi, Javad,Tajbakhsh, Mahmood,Bamoniri, Abdolhamid,Parach, Ali
, p. 318 - 321 (2007/10/03)
The production of triazinyl fluorescent brightener intermediates in high yields is described. The method involves a simplified work-up for the preparation of 4-nitro-toluene-2-sulfonic acid and the use of diethylene glycol instead of water in the preparation of 4,4′-dinitrostilbene-2,2′- disulfonic acid.
Aryl sulfonic acids and derivatives as FSH antagonists
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, (2008/06/13)
This invention provides compounds of formula I having the structure wherein R1, Ar, Ar′, and Q are as defined in the specification, or a pharmaceutically acceptable salt thereof, which are useful as contraceptive agents.
Structural volume changes upon photoisomerization: A laser-induced optoacoustic study with a water-soluble nitrostilbene
Michler, Ingolf,Feis, Alessandro,Rodriguez, Miguel A.,Braslavsky, Silvia E.
, p. 4814 - 4821 (2007/10/03)
The trans to cis photoisomerization of 4,4′-dinitro-2,2′-disulfonylstilbene (DS) was studied by laser-induced optoacoustic spectroscopy (LIOAS) in aereated neat water and in aereated aqueous solutions of various monovalent cations (NH4+, N(CH3)4+, Na+, K+, and Cs+) and the respective cis to trans photoisomerization only in the presence of NH4+. In every case, two single-exponential components were required to fit the data, one with an unresolved lifetime (3p* in equilibrium with the lowest trans triplet state 3t*) and one with a longer lifetime of (75 ± 20) ns at 5.5 °C for the decay of the T mixture. The temperature dependence of the LIOAS amplitudes in combination with the determined isomerization quantum yields afforded a contraction of -(1.4 ± 0.15) ml/mol for the trans to T transition, whereas a smaller contraction of -(0.15 ± 0.15) ml/mol was obtained for the cis to T transition. The different values of the contraction indicate a greater similarity between the average structures of the T components with the cis ground singlet state than with the trans ground singlet. The total structural volume change for the trans to cis transition is in average ΔVtc = - (1.2 ± 0.1) ml/mol. The calculated contribution of electrostriction is at most 50% of this value. However, the nature of the countercation had no influence on the data as would be expected for changes in the specific interaction with the H-bond network in water upon photoisomerization. Thus, ca. 50% of the total contraction is attributed to intrinsic effects, related to a shorter C=C bond and a smaller accessible volume in the cis isomer. The LIOAS data show that cis-DS lies (28 ± 35) kJ/mol above trans-DS in agreement with the calculated value of 37 kJ/mol.
Continuous reduction process
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, (2008/06/13)
A process for the reduction of aromatic nitro compounds to amino compounds in the liquid phase using iron as reducing agent, which comprises carrying out the reduction continuously such that the reducing iron, based on the amount of nitro compound present in the reactor, is present in an amount substantially in excess of the stoichiometric amount, and effecting the continuous removal of the reaction products such that the substantial excess of reducing iron is also constantly present in the reactor during the reduction.
INVESTIGATIONS IN THE REGION OF AROMATIC DISULFIDES. X. SYNTHESIS AND PROPERTIES OF STILBENE 2,2'-DISULFIDE AND ITS DERIVATIVES
Zheltov, A. Ya.,Avramenko, E. N.,Stepanov, B. I.
, p. 342 - 347 (2007/10/02)
The previously undescribed stilbene 2,2'-disulfide, bibenzyl 2,2'-disulfide, and a series of their derivatives were synthesized in order to study the character of electronic interaction between the S-S group and the ? system of stilbene.On the basis of th
