128052-77-7

Basic information

• Product Name: (2S,3S,6R,10bR)-6-Ethyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one
• CAS NO: 128052-77-7
• Molecular Weight: 351.445
• Mol File: 128052-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,6R,10bR)-6-Ethyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,6R,10bR)-6-Ethyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one(128052-77-7)
• EPA Substance Registry System: (2S,3S,6R,10bR)-6-Ethyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one(128052-77-7)

Safety Data

• Hazardous Substances Data: 128052-77-7(Hazardous Substances Data)

Upstream product

• 83-33-0 inden-1-one 
• 127998-41-8 (2S,3S,10bR)-3-Hydroxymethyl-10b-methyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 195871-32-0 2-(2-acetylphenyl)acetaldehyde 
• 36073-90-2 2-(2-acetylphenyl)acetic acid 
• 64666-42-8 1-methyl-1-indanol 
• 767-60-2 3-Methylindene 
• 127998-42-9 (2S,3S,10bR)-3-Hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Asymmetric Synthesis of 4,4-Disubstituted 1-Naphthalenones. Diastereoselectivity as a Function of Metal Oxides

Chiral tricyclic lactam (5) was sequentionally metalated (LDA or LDA/zirconocene halides) and alkylated to give quaternary alkylation products (8) in 6-54:1 diastereomeric ratio.Reduction and hydrolysis furnish the title compound in three steps with >99 p