1280582-84-4

Basic information

• Product Name: C₁₅H₁₁BrCl₂O
• Synonyms: C₁₅H₁₁BrCl₂O
• CAS NO: 1280582-84-4
• Molecular Weight: 358.062
• Mol File: 1280582-84-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₁BrCl₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₁BrCl₂O(1280582-84-4)
• EPA Substance Registry System: C₁₅H₁₁BrCl₂O(1280582-84-4)

Safety Data

• Hazardous Substances Data: 1280582-84-4(Hazardous Substances Data)

Upstream product

• 108-88-3 toluene 
• 19719-28-9 2,4-dichlorophenylacetic acid 
• 144952-05-6 2-(2,4-dichlorophenyl)-1-(p-tolyl)ethanone 

Downstream Products

• 1370024-36-4 2-(2,4-dichlorophenyl)-3-(4-methylphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxylic acid 
• 1370409-54-3 2-(2,4-dichlorophenyl)-3-(4-methylphenyl)-7-nitroimidazo[2,1-b][1,3]benzothiazole 
• 1370024-90-0 2-(2,4-dichlorophenyl)-3-(4-methylphenyl)-5-nitroimidazo[2,1-b][1,3]benzothiazole 

Relevant articles and documents

Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2, 1, b]-benzothiazole derivatives

A novel series of substituted diaryl imidazo[2, 1-b]benzothiazole derivatives (8a-y) were synthesized by condensation reaction between 2-amino benzothiazole derivatives (3a-g) and substituted a-bromo-1, 2-(substituted) diaryl-1-ethanones (7a-i). The structures of the synthesized compounds were established by IR, 1H NMR, 13C NMR and mass spectroscopical data. The compounds (8a-y) were evaluated for their in-vitro cytotoxic activity on murine (B16F10) and human (MCF-7) cancer cells by using MTT assay. From the in vitro studies compounds 8p, 8u and 8y were found most effective with an IC50 range of 0.56-27.50 μM in MCF-7 and 2.57-36.54 μM in B16F10 cells.