128120-93-4Relevant articles and documents
NOVEL BENZIMIDAZOLE DERIVATIVES
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Paragraph 0186, (2020/01/22)
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Synthesis method of starting raw material for daclatasvir
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Paragraph 0022; 0025, (2018/05/16)
The invention relates to a synthesis method of a starting raw material for daclatasvir. The synthesis method comprises the following steps of enabling 2,4'-dibromoacetophenone as shown in a formula I,L-BOC-proline as shown in a formula II, potassium carbo
Hepatitis c polymerase inhibitors
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, (2017/08/25)
The invention relates to a 4,4'-bis(2-((S)-pyrrolidine-2-yl)-1H-imidazole-4-yl)biphenyl type compound and a derivative therefore. The compound disclosed by the invention is a hepatitis c virus (HCV) polymerase inhibitor, has HCV resistant activity and can