128207-11-4

Upstream product

• 2050-44-4 N-(2,5-dimethylphenyl)acetamide 
• 20782-94-9 4-chloro-2,5-dimethylaniline 
• 56961-88-7 N-(4-chloro-3-methylphenyl)acetamide 
• 112359-25-8 5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate 
• 15719-64-9 methylammonium carbonate 

Downstream Products

• 860580-53-6 acetic acid-(4-chloro-3,6-dimethyl-2-nitro-anilide) 
• 854824-49-0 4-Chloro-3,6-dimethyl-2-nitroaniline 

Relevant academic research and scientific papers

Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas

A novel method for the ortho alkylation of acetanilide and aromatic urea derivatives via C-H activation was developed. Alkyl dibenzothiophenium salts are considered to be new reagents for the palladium-catalyzed C-H activation reaction, which enables the transfer of methyl and other alkyl groups from the sulfonium salt to the aniline derivatives under mild catalytic conditions.