128237-20-7

Upstream product

• 637-69-4 4-Methoxystyrene 
• 96045-14-6 cis-1-cyano-2-(4-methoxyphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene 
• 56437-05-9 1-cyano-4-methoxybenzocyclobutane 

Downstream Products

• 128237-23-0 (3aR*,4R*,10aR*)-4-(4'-methoxyphenyl)-1-propyl-3,3a,4,5,6,8-hexahydrocyclopentanaphthalene-3,8-dione 
• 128237-21-8 (3aR*,4R*,10aR*)-4-(4'-methoxyphenyl)-1-phenyl-3,3a,4,5,6,8-hexahydrocyclopentanaphthalene-3,8-dione 

Relevant academic research and scientific papers

Applications of the spiroannulation of tetralins with alkynes; towards new anti-estrogenic compounds

Thermal reaction of the benzocyclobutene 17 with 4-methoxystyrene leads to 1-cyano-2-(4-methoxyphenyl)-6-methoxytetralin? 19 through an electrocyclic ring opening Diels-Alder sequence: the derived acid chloride 20, and its analogue 10, then undergoes an u

Synthesis of Tricyclospirodienones via Spiroannulation; Methodology for Synthesis of Aromatase Inhibitors

A new approach to the title ring system, required for the development of potential aromatase inhibitors, is described; acid chlorides (6) and (12) undergo an unusual addition-cyclisation reaction with alkynes, catalysed by aluminium chloride, to yield tri