128253-65-6

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 

Downstream Products

• 82326-69-0 (R)-1-azabicyclo<2.2.2>-oct-3-yl-(R,S)-α-hydroxy-α-(4-bromophenyl)-α-phenylacetate 
• 82326-69-0 (S)-1-azabicyclo<2.2.2>-oct-3-yl-(R,S)-α-hydroxy-α-(4-bromophenyl)-α-phenylacetate 

Relevant academic research and scientific papers

Stannylated 3-quinuclidinyl benzilates and methods of preparing radiohalogenated derivatives

The present invention provides stannylated 3-quinuclidinyl benzilate compounds and a method of synthesizing *AQNB by iodinating such stannylated 3-quinuclidinyl benzilate compounds. The iodination of these stannylated 3-quinuclidinyl benzilates proceeds in as little as five minutes; thus, the stannylated 3-quinuclidinyl benzilates may be converted to *AQNB in situ for immediate use. Using this method, radiolabelling yields as high as 80% have been observed. The present invention also is directed towards a method of synthesis of the stannylated 3-quinuclidinyl benzilate compounds. The method comprises providing a 4'-halo-3-quinuclidinyl benzilate and reacting the 4'-halo-3-quinuclidinyl benzilate with a compound having the formula (SnR3)2, wherein R is an alkyl.

Boronic acid adducts of rhenium dioxime and technetium-99m dioxime complexes containing a biochemically active group

Boronic acid adducts of technetium-99m and radioactive rhenium dioxime complexes, each of which include biochemically active groups, are useful as diagnostic and therapeutic agents, respectively.