128286-13-5Relevant academic research and scientific papers
Iobitridol preparation method and iobitridol intermediate and preparation method thereof
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, (2020/04/02)
The invention discloses an iobitridol preparation method and an iobitridol intermediate and a preparation method thereof, and specifically relates to an intermediate M1 5-(2-isopropyl-1,3-dioxane-5-carbonylacyl)-2,4,6-triiodo isophthalic acid for preparing iobitridol. The invention also discloses a preparation method of the intermediate M1 and a method for preparing iobitridol from the intermediate M1. The intermediate is high in activity and easy to prepare, and the method for synthesizing iobitridol from the intermediate is short in time, simple in synthesis method, low in comprehensive costand high in the yield and the purity of the reaction target object, and is suitable for industrial production.
Preparation method for non-ionic iodine contrast agent intermediate
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Paragraph 0007; 0022-0041, (2019/01/08)
The invention specifically relates to a preparation method for a non-ionic iodine contrast agent intermediate, belonging to the field of medical chemistry. The preparation method comprises the following steps: step 1) reacting a compound as shown in a for
Novel iodinated non-ionic triiodobenzene compounds and contrast media containing them
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, (2008/06/13)
The invention relates to novel non-ionic compounds of formula STR1 These compounds can be used as contrast media.
