154921-11-6

Basic information

• Product Name: DIMETHYL 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLATE
• Synonyms: DIMETHYL 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLATE;dimethyl 5-amino-2,4,6-triiodoisophthalate
• CAS NO: 154921-11-6
• Molecular Formula: C₁₀H₈I₃NO₄
• Molecular Weight: 586.88823
• Mol File: 154921-11-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 500.4±50.0 °C(Predicted)
• Appearance: /
• Density: 2.511±0.06 g/cm3(Predicted)
• PKA: -2.61±0.10(Predicted)
• CAS DataBase Reference: DIMETHYL 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLATE(154921-11-6)
• EPA Substance Registry System: DIMETHYL 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLATE(154921-11-6)

Safety Data

• Hazardous Substances Data: 154921-11-6(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 35453-19-1 2,4,6-triiodo-5-aminoisophthalic acid 
• 99-31-0 5-aminoisophthalic acid 
• 67-56-1 methanol 

Downstream Products

• 1026150-94-6 2,4,6-Triiodo-5-isocyanato-isophthalic acid dimethyl ester 
• 166818-05-9 Dimethyl 2,4,6-triiodo-5-<(1-oxo-4-pentenoyl)amino>-1,3-benzenedicarboxylate 
• 182758-19-6 5-(3-Bromo-2-oxo-pyrrolidin-1-yl)-2,4,6-triiodo-isophthalic acid dimethyl ester 
• 182758-13-0 5-(2,5-Dibromo-pentanoylamino)-2,4,6-triiodo-isophthalic acid dimethyl ester 
• 73334-07-3 iopromide 
• 136949-58-1 iobitridol 
• 154921-12-7 dimethyl 2,4,6-triiodo-5-<<(oxiranylmethoxy)carbonyl>amino>-1,3-benzenedicarboxylate 
• 182758-06-1 5-(3-Acetoxy-2-oxo-piperidin-1-yl)-2,4,6-triiodo-isophthalic acid dimethyl ester 
• 182758-21-0 5-(3-Acetoxy-2-oxo-pyrrolidin-1-yl)-2,4,6-triiodo-isophthalic acid dimethyl ester 
• 182758-05-0 5-(3-Bromo-2-oxo-piperidin-1-yl)-2,4,6-triiodo-isophthalic acid dimethyl ester 

Relevant articles and documents

Preparation method of iopromide

The invention belongs to the technical field of chemical synthesis, and particularly relates to a preparation method of iopromide. The method comprises the steps that 5-amino-2,4,6-triiodo isophthalic acid is adopted as a raw material to obtain diester to react with methoxyacetyl chloride, and the product is subjected to an ester ammonolysis reaction with side-chain 3-amino propylene glycol and 3-methylamino propylene glycol respectively to obtain iopromide. The preparation method of the iopromide, a catalyst and a by-product methyl alcohol can be removed only through solvent crystallization, green production can be achieved, no industrial wastewater or waste gases or residues exist, and the preparation method is particularly suitable for preparing iopromide in industrial mass production.