128311-08-0

Basic information

• Product Name: S(-)-4-chloro-N-(3-quinuclidinyl)benzamide hydrochloride
• CAS NO: 128311-08-0
• Molecular Weight: 301.216
• Mol File: 128311-08-0.mol

Chemical Properties

• CAS DataBase Reference: S(-)-4-chloro-N-(3-quinuclidinyl)benzamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: S(-)-4-chloro-N-(3-quinuclidinyl)benzamide hydrochloride(128311-08-0)
• EPA Substance Registry System: S(-)-4-chloro-N-(3-quinuclidinyl)benzamide hydrochloride(128311-08-0)

Safety Data

• Hazardous Substances Data: 128311-08-0(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 74-11-3 para-chlorobenzoic acid 

Relevant articles and documents

Method of treating or preventing schizophrenia and/or psychosis using S-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides

Compounds of general formula I STR1 wherein: X represents oxygen or sulphur; each of R1 and R3 independently represents hydrogen or a C1 -C4 alkyl group; Ar represents: a phenyl ring optionally substituted by one, two or three C1 -C4 alkoxy groups and/or by one or two halogen atoms; a phenyl ring of the general formula STR2 wherein R2 represents halogen, 4,5-benzo, C1 -C8 alkoxy, C1 -C4 alkylcarbonyl or Am, wherein Am represents amino, methylamino or dimethylamino, R4 represents C1 -C8 alkyl, n is 1 or 2; or a pyrimidinyl moiety of the general formula STR3 wherein R5 is C1 -C4 alkyl; and their N-oxides and pharmaceutically acceptable salts are useful as antischizophrenic and/or antipsychotic agents. A preferred compound is S(-)-4-amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxybenzamide.