128344-67-2Relevant academic research and scientific papers
Cyclomanganation of diterpenoids; functionalization of C14
Cambie, Richard C.,Metzler, Michael R.,Rutledge, Peter S.,Woodgate, Paul D.
, p. C26 - C30 (1990)
Orthomanganated complexes have been made from carbonyl derivatives of the ring-C aromatic diterpenoids podocarpic acid and dehydroabietic acid.Activation of these complexes with Me3NO followed by coupling reactions with various substituted alkenes results in efficient substitution at C14.In some cases a tetracyclic indenol derivative is formed directly.Insertion of an alkyne also leads to cyclopentaannulation.
Coupling reactions of diterpenoid η2-tetracarbonylmanganese complexes with alkynes
Cambie, Richard C.,Metzler, Michael R.,Rutledge, Peter S.,Woodgate Paul D.
, p. 41 - 57 (2007/10/02)
A number of tetracarbonylmanganese complexes derived from podocarpic acid (1) have heen coupled with acetylene or diphenylacetylene to give steroidal analogues in high yield.Several modes of activating these manganese complexes towards coupling reactions
