1283689-49-5

Basic information

• Product Name: 4-{4-[(1R,2R)-2-(methanesulphonyl-methyl-amino)cyclopentyloxy]-5-trifluoromethyl-pyrimidin-2-ylamino}-3-methoxy-N-(1-methyl-piperidin-4-yl)benzamide
• Synonyms: 4-{4-[(1R,2R)-2-(methanesulphonyl-methyl-amino)cyclopentyloxy]-5-trifluoromethyl-pyrimidin-2-ylamino}-3-methoxy-N-(1-methyl-piperidin-4-yl)benzamide
• CAS NO: 1283689-49-5
• Molecular Weight: 586.635
• Mol File: 1283689-49-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-{4-[(1R,2R)-2-(methanesulphonyl-methyl-amino)cyclopentyloxy]-5-trifluoromethyl-pyrimidin-2-ylamino}-3-methoxy-N-(1-methyl-piperidin-4-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{4-[(1R,2R)-2-(methanesulphonyl-methyl-amino)cyclopentyloxy]-5-trifluoromethyl-pyrimidin-2-ylamino}-3-methoxy-N-(1-methyl-piperidin-4-yl)benzamide(1283689-49-5)
• EPA Substance Registry System: 4-{4-[(1R,2R)-2-(methanesulphonyl-methyl-amino)cyclopentyloxy]-5-trifluoromethyl-pyrimidin-2-ylamino}-3-methoxy-N-(1-methyl-piperidin-4-yl)benzamide(1283689-49-5)

Safety Data

• Hazardous Substances Data: 1283689-49-5(Hazardous Substances Data)

Upstream product

• 869937-03-1 4-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}-3-methoxybenzoic acid 
• 41838-46-4 4-Amino-1-methylpiperidine 
• 1283691-19-9 4-[4-((1R,2R)-2-amino-cyclopentyloxy)-5-trifluoromethyl-pyrimidin-2-ylamino]-3-methoxy-N-(1-methyl-piperidin-4-yl)-benzamide 
• 124-63-0 methanesulfonyl chloride 

Relevant articles and documents

PYRIMIDINE DERIVATIVES AS PROTEIN TYROSINE KINASE 2 INHIBITORS

The present invention encompasses compounds of general formulae (1a) and (1b), wherein the groups R1 to R5, A, Q, m, n, p and q are defined as in claim 1, which are FAK/PTK2 inhibitors and thus suitable for the treatment of diseases