128372-51-0Relevant academic research and scientific papers
Palladium-catalyzed arylation of the THP derivative of (Z)-2-butene-1,4- diol with arenediazonium salts and the synthesis of β-aryl-γ- butyrolactones
Cacchi, Sandro,Fabrizi, Giancarlo,Goggiamani, Antonella,Sferrazza, Alessio
, p. 973 - 977 (2009)
The reaction of arenediazonium tetrafluoroborates with the THP derivative of (Z)-2-butene-l,4-diol in the presence of Pd(OAc)2 in MeOH at 35 °C gives 4-aryl-2-mefhoxytetrahydrofurans in good to high yields. The reaction tolerates a variety of u
Synthesis of quaternary carbon centers via hydroformylation
Sun,Frimpong,Tan
supporting information; experimental part, p. 11841 - 11843 (2010/11/04)
The application of hydroformylation to the synthesis of quaternary carbon centers is reported. The synthesis of the highly substituted carbon is achieved by applying a catalytic amount of 1. Ligand 1 serves as a catalytic directing group by covalently and reversibly binding to both the substrate and catalyst. The intramolecular nature of the directing group strategy accelerates the hydroformylation reaction such that the reaction is performed at mild temperatures (35-55 °C) and with excellent regioselectivity (b:l > 94:6).
