46333-28-2Relevant articles and documents
Synthesis of quaternary carbon centers via hydroformylation
Sun,Frimpong,Tan
supporting information; experimental part, p. 11841 - 11843 (2010/11/04)
The application of hydroformylation to the synthesis of quaternary carbon centers is reported. The synthesis of the highly substituted carbon is achieved by applying a catalytic amount of 1. Ligand 1 serves as a catalytic directing group by covalently and reversibly binding to both the substrate and catalyst. The intramolecular nature of the directing group strategy accelerates the hydroformylation reaction such that the reaction is performed at mild temperatures (35-55 °C) and with excellent regioselectivity (b:l > 94:6).
Regioselective Heck arylation of unsaturated alcohols by palladium catalysis in ionic liquid
Mo, Jun,Xu, Lijin,Ruan, Jiwu,Liu, Shifang,Xiao, Jianliang
, p. 3591 - 3593 (2008/09/20)
In contrast to almost all of the known examples of Heck arylation of unsaturated alcohols, which yield predominately β-arylated products, arylation under the Pd-DPPP catalysis in ionic liquid leads preferentially to aryl substitution at the α carbon, prov
Mechanistic studies of an antibody-catalyzed pericyclic rearrangement
Driggers, Edward M.,Cho, Ho S.,Liu, Corey W.,Katzka, Catherine P.,Braisted, Andrew C.,Ulrich, Helle D.,Wemmer, David E.,Schultz, Peter G.
, p. 1945 - 1958 (2007/10/03)
We report NMR and kinetic studies of antibody AZ-28, which was generated against the diaryl-substituted cyclohexanol derivative 3 and catalyzes the oxy-Cope rearrangement of the corresponding hexadiene 1 to aldehyde 2 (Braisted, A. C., Schultz, P. G. J. A
