128373-65-9

Upstream product

• 100-39-0 benzyl bromide 
• 80532-35-0 (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 81703-94-8 methyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 

Downstream Products

• 128373-67-1 (2S),(Z)-5-benzyloxy-3-pentene-1,2-diol 
• 201230-90-2 (S)-4-((1S,3R)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2,2-dimethyl-[1,3]dioxolane 
• 201230-89-9 (S)-4-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2,2-dimethyl-[1,3]dioxolane 
• 128373-69-3 (2S),(Z)-5-benzyloxy-1-tosyloxy-3-penten-2-ol 
• 128442-96-6 (2S),(Z)-5-benzyloxy-1,2-epoxy-3-pentene 
• 201231-35-8 [(R)-2-Azido-2-((1R,3S)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 201231-43-8 [(S)-2-Azido-2-((1R,3S)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 201231-50-7 [(R)-2-Azido-2-((1S,3R)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 201231-58-5 [(S)-2-Azido-2-((1S,3R)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 344359-02-0 (R)-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-46-1 (S)-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-53-0 (R)-((1S,3R)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-61-0 (S)-((1S,3R)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-45-0 [(S)-1-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

STEREOSELECTIVE SN2' ADDITIONS OF ORGANOCUPRATES TO HOMOCHIRAL ACYLIC VINYLOXIRANES

Additions of various methylcopper reagents to the homochiral acylic vinyloxiranes A14, A15, B6-B9, and C5, C6 were performed in order to evaluate E/Z and syn/anti preferences.The unsubstituted oxiranes A14 and A15 gave a mixture of SN2 and SN2' substitution products with the four reagents examined, LiMe2Cu, LiMeCuCN, BrMgMe2Cu, and LiMeCuI*BF3.The more highly substituted systems B6-B9 derived from geraniol and C5, C6 derived from nerol yielded only SN2' products.The (Z)-allylic alcohol derivatives B8 and C6 and LiMeCuCN gave the best anti/syn ratios (99:1 and 97:3, respectively).In both cases the newly formed double bond was exclusively E.