201230-89-9

Upstream product

• 1895-39-2 sodium chlorodifluoroacetate 
• 128373-65-9 (4S),(Z)-1-benzyloxy-4,5-(isopropylidenedioxy)-2-pentene 

Downstream Products

• 201231-35-8 [(R)-2-Azido-2-((1R,3S)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 201231-43-8 [(S)-2-Azido-2-((1R,3S)-3-benzyloxymethyl-2,2-difluoro-cyclopropyl)-ethoxy]-tert-butyl-dimethyl-silane 
• 344359-02-0 (R)-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-46-1 (S)-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-tert-butoxycarbonylamino-acetic acid methyl ester 
• 201231-45-0 [(S)-1-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 201231-37-0 [(R)-1-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 201231-42-7 (R)-1-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2-(tert-butyl-dimethyl-silanyloxy)-ethanol 
• 201231-34-7 (S)-1-((1R,3S)-3-Benzyloxymethyl-2,2-difluoro-cyclopropyl)-2-(tert-butyl-dimethyl-silanyloxy)-ethanol 

Relevant academic research and scientific papers

Preparation of difluoro analogs of CCGs and their pharmacological evaluations

All the stereoisomers of 2-(2-carboxy-3,3-difluorocyclopropyl)glycines (F2CCGs) were synthesized in enantiomerically pure forms using (R)-2,3-O- isopropyl-ideneglyceraldehyde as a chiral precursor. L-F2CCG-I, one of the stereoisomers