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1284258-80-5

1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1284258-80-5 Structure

  • Basic information

    1. Product Name: 1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one
    2. Synonyms: 1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one
    3. CAS NO:1284258-80-5
    4. Molecular Formula:
    5. Molecular Weight: 399.277
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1284258-80-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one(1284258-80-5)
    11. EPA Substance Registry System: 1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one(1284258-80-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1284258-80-5(Hazardous Substances Data)

1284258-80-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1284258-80-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,4,2,5 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1284258-80:
(9*1)+(8*2)+(7*8)+(6*4)+(5*2)+(4*5)+(3*8)+(2*8)+(1*0)=175
175 % 10 = 5
So 1284258-80-5 is a valid CAS Registry Number.

1284258-80-5Relevant articles and documents

CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID

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Page/Page column 25, (2012/01/03)

A process for synthesizing and screening solution phase derived libraries of fenbufen and ethacrynic acid is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.

Solution-phase parallel synthesis and screening of anti-tumor activities from fenbufen and ethacrynic acid libraries

Su, Yuan-Hsiao,Chiang, Li-Wu,Jeng, Kee-Ching,Huang, Ho-Lien,Chen, Jenn-Tzong,Lin, Wuu-Jyh,Huang, Chia-Wen,Yu, Chung-Shan

supporting information; experimental part, p. 1320 - 1324 (2011/04/16)

The derivatives with fenbufen and ethacrynic acid core compounds was synthesized through a facial preparation of 1-amino-4-azidobutane. The subsequent coupling with 102 members of carboxylic acids afforded amide products. The in situ screening using colorimetric assay with 3-(4.5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide showed that fenbufen but not ethacrynic acid butyl amide members displayed the cytotoxicities to tumor cells substantially, including two human cell lines (MCF7 and A549) and two murine cell lines (C26 and TRAMP-C1). Three fenbufen analogs were found to have a good anti-tumor activity comparable to cisplatin.

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