128441-46-3

Upstream product

• 142130-93-6 ((3R,5S)-3,5-Dimethyl-cyclohex-1-enyloxy)-trimethyl-silane 
• 284046-14-6 (5R)-1,5-dimethyl-2-cyclohexen-1-ol 
• 89-82-7 pulegone 
• 56764-09-1 1,5-dimethyl-2-(1-methylethylidene)cyclohexan-1-ol 
• 284046-13-5 (4R)-2-hydroxy-2,4-dimethyl-1-cyclohexanone 
• 7214-52-0 3,5-dimethyl-cyclohexanone 
• 5526-47-6 4-methyl-heptane-2,6-dione 

Downstream Products

• 443883-72-5 (1S,5S)-3,5-Dimethyl-cyclohex-2-enol 
• 866931-93-3 tert-Butyl-((1S,5S)-3,5-dimethyl-cyclohex-2-enyloxy)-diphenyl-silane 
• 866931-99-9 Acetic acid (1S,4R,6S)-6-(tert-butyl-diphenyl-silanyloxy)-2,4-dimethyl-cyclohex-2-enyl ester 
• 866931-95-5 (1S,2R,3S,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-1,5-dimethyl-cyclohexane-1,2-diol 
• 866931-96-6 Acetic acid (1R,2S,4R,6S)-6-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-2,4-dimethyl-cyclohexyl ester 
• 335101-30-9 (1S,2R,5R)-1,2-dihydroxy-3,5-dimethyl-3-cyclohexene 
• 443883-50-9 (1S,2R,5R)-1,2-di[(tert-butyldimethylsilyl)oxy]-3,5-dimethyl-3-cyclohexene 
• 2320-30-1 (3S)-3r,5t-dimethyl-cyclohexanone 

Relevant academic research and scientific papers

Primary-amine-catalyzed enantioselective intramolecular aldolizations

Aldol cyclodehydration of 4-substituted-2,6-heptanediones leads to enantiomerically enriched 5-substituted-3-methyl-2-cyclohexene-1-ones, which serve as perfume ingredients and valuable synthetic building blocks.Primary amines derived from cinchona alkalo

Synthetic studies of the HIV-1 protease inhibitive didemnaketals: stereocontrolled synthetic approach to the key mother spiroketals.

The stereocontrolled synthesis of (2S,4R,6R,8S,10S,1'R,1' 'R)-2(acetylhydroxymethyl)-4,10-dimethyl-8(isopropenylhydroxymethyl)-1,7-dioxaspiro[5,5]undecane (4a) and its C1' '-epimer (4b), the key mother spiroketals of the HIV-1 protease inhibitive didemnaketals from the ascidian Didemnum sp., has been carried out through multisteps from the natural (R)-(+)-pulegone, which involved the diastereoselective construction of four chiral carbon centers(C-2, C-6, C-8, and C-1') by intramolecular chiral induce.

ENANTIOSELECTIVE DEPROTONATION OF THE MESO-FORMS OF 2,6- AND 3,5-DIMETHYLCYCLOHEXANONES

Kinetic deprotonation of meso-dimethylcyclohexanones (1a-c) by chiral lithium amides (2a-c) in the presence of excess trimethylsilyl chloride afforded the corresponding silyl enol ethers (3a-b) in good yields and in reasonably high enantiomeric excesses.