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5-Methoxypodophyllotoxin is a naturally occurring chemical compound derived from the podophyllotoxin found in the Podophyllum genus of plants, particularly the mayapple plant. It is a lignan, a type of organic compound that is structurally related to lignin, and is known for its cytotoxic properties. 5-methoxypodophyllotoxin has been extensively studied for its potential use in cancer treatment due to its ability to inhibit cell division and disrupt the microtubules within cells, which are essential for cell growth and replication. The addition of a methoxy group to the podophyllotoxin molecule enhances its solubility and bioavailability, making it a promising candidate for pharmaceutical development. However, it is important to note that 5-methoxypodophyllotoxin is also associated with significant side effects, and its use in medicine is carefully regulated.

128443-52-7

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128443-52-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 128443-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,4,4 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 128443-52:
(8*1)+(7*2)+(6*8)+(5*4)+(4*4)+(3*3)+(2*5)+(1*2)=127
127 % 10 = 7
So 128443-52-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H24O9/c1-26-13-5-10(6-14(27-2)20(13)28-3)16-11-7-15-21(32-9-31-15)22(29-4)18(11)19(24)12-8-30-23(25)17(12)16/h5-7,12,16-17,19,24H,8-9H2,1-4H3/t12-,16+,17-,19+/m0/s1

128443-52-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (5R,5aR,8aR,9R)-5-hydroxy-4-methoxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one

1.2 Other means of identification

Product number -
Other names 5-methoxypodophyllotoxin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128443-52-7 SDS

128443-52-7Relevant academic research and scientific papers

The large-scale isolation of deoxypodophyllotoxin from rhizomes of Anthriscus sylvestris followed by its bioconversion into 5- methoxypodophyllotoxin β-D-glucoside by cell cultures of Linum flavum

Van Uden, Wim,Bos, Jeroen A.,Boeke, Gesiena M.,Woerdenbag, Herman J.,Pras, Niesko

, p. 401 - 403 (2007/10/03)

Dried rhizomes of Anthriscus sylvestris contained 0.39% deoxypodophyllotoxin (1). An isolation procedure with an extraction efficiency of 51.2% was developed for this commercially unavailable lignan. The isolated 1 was subsequently complexed with dimethyl

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