128466-45-5Relevant academic research and scientific papers
Enantiospecific synthesis of (R)- and (S)-2,3-diaminopropanol from L- and D-serine
Demirci, Fatih,Haines, Alan H.,Jia, Chunhua,Wu, Di
, p. 189 - 191 (2007/10/03)
Both chiral forms of 2,3-diaminopropanol (6) have been prepared in a convenient 5-step synthesis based on the readily available N-benzyloxycarbonyl derivatives of the methyl esters of L- and D-serine.
Convenient preparation of O-benzyl-N-Cbz-D-serinol, an intermediate in β-hydroxy-α-amino acid synthesis
Monache,Di Giovanni,Maggio,Misiti,Zappia
, p. 1155 - 1158 (2007/10/02)
A convenient preparation of (2S)-3-benzyloxy-2-[(benzyloxycarbonyl)amino]propanol (2) in 52% yield, employing cheap L-serine as starting material, is described. Conversion of 2 into methyl (2Z,4R)-5-benzyloxy-4-[(benzyloxycarbonyl)amino]pent-2-enoate (1) is reported.
Convenient preparation of (R)- and (S)-1-(2-amino-3-iodo)propanol derivatives from (S)-serine: Application in radical addition reactions
Maria,Da Silva,Fourrey,Machado,Robert-Gero
, p. 3301 - 3302 (2007/10/02)
An efficient three step synthesis of the (R)- and (S)-1-(2-amino-3-iodo)propanol derivatives 4 and 7 from (S) serine is proposed. Their use in radical reactions is illustrated.
SYNTHESIS OF THE HOMOCHIRAL "TRICYCLIC HEART" OF MANZAMINE A
Brands, Karel M. J.,Meekel, Arthur A. P.,Pandit, Upendra K.
, p. 2005 - 2026 (2007/10/02)
An expedient and enantiospecific synthesis of a strategically functionalized tricyclic intermediate for the construction of manzamine A is described.
Synthesis of an optically active tricyclic intermediate for manzamines
Brands, Karel M.J.,Pandit, Upendra K.
, p. 257 - 261 (2007/10/02)
L-Serine has been converted into a chiral pyrroloisoquinoline derivative which can serve as a potential intermediate for manzamines.
