71811-26-2

Usage

Uses

Used in Pharmaceutical Industry:
N-Cbz-2-Amino-1,3-propanediol is used as a chiral building block for the production of pharmaceuticals, contributing to the development of new drugs with improved efficacy and selectivity. Its chiral nature allows for the creation of enantiomerically pure compounds, which is crucial for the synthesis of biologically active molecules.
Used in Agrochemical Industry:
In the agrochemical industry, N-Cbz-2-Amino-1,3-propanediol serves as a chiral building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its use in this industry helps in the development of more effective and environmentally friendly products.
Used in Organic Synthesis:
N-Cbz-2-Amino-1,3-propanediol is used as a key intermediate in the synthesis of various hetero-aromatic compounds, which are important in the development of new organic compounds with potential applications in various fields.
Used in Chiral Amine Preparation:
N-Cbz-2-Amino-1,3-propanediol is utilized in the preparation of chiral amines, which are essential building blocks in the synthesis of a wide range of biologically active molecules, including pharmaceuticals and agrochemicals.
Used in Asymmetric Synthesis:
N-Cbz-2-Amino-1,3-propanediol is employed as a chiral reagent in asymmetric synthesis, enabling the creation of other chiral molecules with high enantioselectivity. This is crucial for the development of enantiomerically pure compounds with specific biological activities.

InChI:InChI=1/C11H15NO4/c13-6-10(7-14)12-11(15)16-8-9-4-2-1-3-5-9/h1-5,10,13-14H,6-8H2,(H,12,15)

Upstream product

• 501-53-1 benzyl chloroformate 
• 128466-45-5 (R)-4-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester 
• 534-03-2 serinol 

Downstream Products

• 138625-61-3 2-benzyloxycarbonylaminopropenal 
• 1239915-15-1 benzyl 4-(hydroxymethyl)-2-(pyridin-2-yl)oxazolidine-3-carboxylate 
• 1239915-17-3 C₁₇H₁₈N₂O₅ 
• 1239915-14-0 benzyl [2-(pyridin-2-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-11-7 benzyl [2-(pyridin-2-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-29-7 4-[3-(benzyloxycarbonyl)-4-(hydroxymethyl)oxazolidin-2-yl]pyridine 1-oxide 
• 1239915-28-6 benzyl [2-(pyridin-4-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-26-4 benzyl [2-(pyridin-4-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-21-9 benzyl [2-(pyridin-3-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-20-8 benzyl [2-(pyridin-3-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-33-3 benzyl 4-(hydroxymethyl)-2-(1H-pyrrol-2-yl)oxazolidine-3-carboxylate 
• 1239915-37-7 benzyl 2-(furan-2-yl)-4-(hydroxymethyl)oxazolidine-3-carboxylate 
• 1312930-26-9 benzyl [2-(furan-2-yl)-1,3-dioxan-5-yl]carbamate 
• 1239915-35-5 benzyl [2-(furan-2-yl)-1,3-dioxan-5-yl]carbamate 

Relevant academic research and scientific papers

An M2-V27A channel blocker demonstrates potent in?vitro and in?vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses

Adamantanes such as amantadine (1) and rimantadine (2) are FDA-approved anti-influenza drugs that act by inhibiting the wild-type M2 proton channel from influenza A viruses, thereby inhibiting the uncoating of the virus. Although adamantanes have been suc

ADAMANTANE ANALOGS

Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.

Novel 2,5-Disubstituted 1,3-dioxanes and oxazolidines as potential chemoprevention agents and building blocks for organic synthesis

2,5-Disubstituted 1,3-dioxacycloalkanes have recently been found to be promising lead, compounds that possess potent anti-inflammatory activity and therefore may act as chemoprevention agents. Encouraged by this we have designed and synthesized a new seri

Trimethylsilyl trifluoromethanesulfonate (TMSOTf) assisted facile deprotection of N,O-acetonides

(Chemical Equation Presented) Employing TMSOTf as an easily available reagent, we have developed a mild and efficient method for the deprotection of both terminal and internal N,O-acetonide functionalities. Various regularly used protecting groups and com

Highly efficient synthesis of enantiomerically enriched 2-hydroxymethylaziridines by enzymatic desymmetrization

(Chemical Equation Presented) Both enantiomers of protected and unprotected 2-hydroxymethylaziridines are efficiently and enantiospecifically synthesized by using a combination of enzymatic and synthetic methods. PPL was used for lipase-catalyzed desymmet

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE)

Results from a factor analysis and activity studies of commercially available endocannabinoid-type compounds set the starting point for the current study where dimethylheptyl (DMH) analogues of two endocannabinoids, 2-arachidonoyl glycerol (2-AG) and 2-ar

Chemoselective deprotection of cyclic N,O-aminals using catalytic bismuth(III) bromide in acetonitrile

Cyclic N,O-aminals can be chemoselectively and efficiently deprotected using a catalytic amount of bismuth(III) bromide in acetonitrile at room temperature. This selectivity was also achieved in the presence of terminal O,O-acetal functionality. The susce

5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP

5-Carboxamido-1,3,2-dioxaphosphorinanes have been identified as potent inhibitors of microsomal triglyceride-transfer protein. The 1,3,2- dioxaphosphorine functionality acted as a neutral and stable replacement for piperidine and piperidine N-oxide.

Synthesis and mesogenic properties of a Y-shaped glyco-glycero-lipid

We synthesised a new glycoglycerolipid [1,3-di-O-(β-D-glucopyranosyl)- 2-deoxy-2-amino-N-palmitoyl-sn-glycerol] with a Y-shaped structure bearing two sugar head groups and only one fatty acid chain. Instead of an ester linkage between the glycerol and the fatty acid an amido function was introduced. The mesogenic properties were investigated using polarising microscopy and are discussed with respect to similar compounds. The lyotropism was measured using the contact preparation method and small-angle neutron-scattering.

Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase

The invention relates to pyridine derivatives of formula (I), wherein the substituents and symbols are defined as indicated in the description, processes for the preparation thereof, their usage in the preparation of a pharmaceutical composition for the treatment of a disease which responds to an inhibition of angiogenesis, and pharmaceutical compositions containing such compounds.