128531-41-9

Basic information

• Product Name: (2S,5R)-2-<(1R)-1-Benzyloxymethoxyethyl>-2-ethyl-5-formyltetrahydrofuran
• Synonyms: (2S,5R)-2-<(1R)-1-Benzyloxymethoxyethyl>-2-ethyl-5-formyltetrahydrofuran
• CAS NO: 128531-41-9
• Molecular Weight: 292.375
• Mol File: 128531-41-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,5R)-2-<(1R)-1-Benzyloxymethoxyethyl>-2-ethyl-5-formyltetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-2-<(1R)-1-Benzyloxymethoxyethyl>-2-ethyl-5-formyltetrahydrofuran(128531-41-9)
• EPA Substance Registry System: (2S,5R)-2-<(1R)-1-Benzyloxymethoxyethyl>-2-ethyl-5-formyltetrahydrofuran(128531-41-9)

Safety Data

• Hazardous Substances Data: 128531-41-9(Hazardous Substances Data)

Upstream product

• 106286-23-1 (E)-5-((4R,5R)-4-Ethyl-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-1-(4-methoxy-phenyl)-pent-2-en-1-ol 
• 151255-01-5 (E)-5-((4R,5R)-4-Ethyl-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-1-(4-methoxy-phenyl)-pent-2-en-1-one 
• 128531-38-4 3-((4R,5R)-4-Ethyl-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propionaldehyde 
• 151255-01-5 (2E)-5-<(4S,5R)-4-Ethyl-2,2,5-trimethyl-1,3-dioxolan-4-yl>-1-(4-methoxyphenyl)-pent-2-en-1-one 
• 151254-94-3 3-O-Benzyl-5-deoxy-3-C-ethyl-1,2-O-(1-methylethylidene)-α-D-ribofuranose 
• 151255-03-7 (4S,5R)-4,5-Di-tert-butyldimethylsilyloxy-5-ethylhexanal 
• 151254-95-4 3-O-Benzyl-5-deoxy-3-C-ethyl-α-D-ribofuranose 
• 151378-19-7 3-<(4S,5R)-4-Ethyl-2,2,5-trimethyl-1,3-dioxolan-4-yl>propanal 
• 151254-98-7 (4S,5R)-4,5-Dihydroxy-4-ethylhexanoic acid 1,4-lactone 
• 151255-00-4 3-<(4S,5R)-4-Ethyl-2,2,5-trimethyl-1,3-dioxolan-4-yl>propanol 
• 151254-99-8 (4S,5R)-4-Ethyl-1,4,5-hexanetriol 
• 128574-68-5 (2S,5R)-2-Ethyl-2-<(1R)-1-hydroxyethyl>-5-<(1E)-2-(4-methoxyphenyl)ethenyl>tetrahydrofuran 
• 106286-31-1 (2S,5S)-2-Ethyl-5-formyl-2-<(1R)-1-hydroxyethyl>tetrahydrofuran 
• 128574-69-6 (2S,5S)-2-Ethyl-2-<(1R)-1-hydroxyethyl>-5-<(1E)-2-(4-methoxyphenyl)ethenyl>tetrahydrofuran 

Downstream Products

• 131967-62-9 (2S)-2-<(2S,3S,5R)-5-<(2R,5S)-5-((1R)-1-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-ethenyl-3-methyltetrahydrofur-2-yl>butan-1-ol 
• 131927-96-3 (4S)-4-<(2S,3S,5R)-5-<(2R,5S)-5-((1R)-1-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-ethyl-3-methyltetrahydrofur-2-yl>hexan-3-one 
• 152934-49-1 (2R)-2-<(2S,3S,5R)-5-<(2R,5S)-5-((1R)-1-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-ethenyl-3-methyltetrahydrofur-2-yl>butanal 
• 131927-91-8 (3S)-1-<(2R,5S)-<(1R)-1-Benzyloxymethoxyethyl>-5-ethyltetrahydrofur-2-yl>-3-<(4S,5S)-5-ethyl-2,2-dimethyl-1,3-dioxan-4-yl>butan-1-one 
• 152934-48-0 {(S)-2-[(2R,4S,5S,2'R,5'S)-5'-((R)-1-Benzyloxymethoxy-ethyl)-5'-ethyl-4-methyl-2-vinyl-octahydro-[2,2']bifuranyl-5-yl]-butoxy}-tert-butyl-dimethyl-silane 
• 54156-67-1 Isolasalocid A 
• 152934-45-7 (2S)-2-<(2S,3S,5R)-5-<(2R,5S)-5-((1R)-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-<(1E)-2-(4-methoxyphenyl)ethenyl>-3-methyltetrahydrofur-2-yl>butyl tert-butyldimethylsilyl ether 
• 152934-55-9 Benzyl 23-O-benzyloxymethylisolasalocid A 
• 131927-95-2 (2S)-2-<(2S,3S,5R)-5-<(2R,5S)-5-((1R)-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-<(1E)-2-(4-methoxyphenyl)ethenyl>-3-methyltetrahydrofur-2-yl>butan-1-ol 
• 131927-95-2 (2S)-2-<(2S,3S,5S)-5-<(2R,5S)-5-((1R)-Benzyloxymethoxyethyl)-5-ethyltetrahydrofur-2-yl>-5-<(1E)-2-(4-methoxyphenyl)ethenyl>-3-methyltetrahydrofur-2-yl>butan-1-ol 
• 25999-31-9 lasalocid (X 537 A) 
• 131967-60-7 (E)-(S)-3-[(2R,5S)-5-((R)-1-Benzyloxymethoxy-ethyl)-5-ethyl-tetrahydro-furan-2-yl]-5-((4S,5S)-5-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-1-(4-methoxy-phenyl)-hex-1-en-3-ol 
• 41733-86-2 lasalocid benzyl ester 

Relevant articles and documents

Stereoselective Total Synthesis of Polyether Ionophore Antibiotics, Isolasalocid A and Lasalocid A. Part 1. Stereocontrolled Construction of the C Rings (C18-C24) by Acid-Catalyzed Cyclization of p-Methoxyphenylallyl Alcohols

The C18-C24 subunits (11, 12) of isolasalocid A (9) and lasalocid A (10) were synthesized stereoselectively via construction of the tetrahydrofuran and tetrahydropyran rings by acid-catalyzed cyclization of the corresponding p-methoxyphenylallyl alcohols (18, 25). Key words: polyether antibiotic; total synthesis; stereoselective synthesis; tetrahydrofuran; tetrahydropyran; acid-catalyzed cyclization.