128545-15-3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 6089-09-4 4-pentynoic acid 

Downstream Products

• 1260519-16-1 4-(S)-benzyl-5,5-dimethyl-3-(5-trimethylsilanylpent-4-ynoyl)-oxazolidin-2-one 
• 1260519-23-0 4-(S)-benzyl-5,5-dimethyl-3-(2-(R)-methyl-5-trimethylsilanyl-pent-4-ynoyl)-oxazolidin-2-one 
• 1260519-17-2 4-(S)-benzyl-5,5-dimethyl-3-(2-(S)-methyl-5-trimethylsilanyl-pent-4-ynoyl)-oxazolidin-2-one 
• 1260519-20-7 4-(S)-isopropyl-5,5-dimethyl-3-(2-(S)-phenethyl-5-trimethylsilanyl-pent-4-ynoyl)-oxazolidin-2-one 
• 1261430-05-0 C₁₈H₂₇NO₂Si 
• 6089-09-4 4-pentynoic acid 

Relevant academic research and scientific papers

Silylation of 1-Alkynes with Chlorosilanes Promoted by Zinc: Preparation of Alkynylsilanes in a Single Step

The direct silylation of 1-alkynes with chlorosilanes smoothly takes place in the presence of zinc powder in acetonitrile, giving good yields of alkynylsilanes.The reactions are tolerant of a wide range of functionalities such as carboxylic acid, ester, alcohol, and chlorine in the 1-alkynes.