1285572-54-4

Upstream product

• 3336-41-2 3,5-dichloro-4-hydroxybenzoic acid 
• 59595-92-5 chlorure de dichloro-3,5 hydroxy-4 benzoyle 
• 75-11-6 diiodomethane 
• 1285573-42-3 3-(3,5-dichloro-4-methoxybenzoyl)-1,2-dihydro-3H-1,3-benzothiazole 
• 29568-76-1 3,5-Dichloro-4-methoxybenzoyl chloride 
• 137-07-5 2-amino-benzenethiol 
• 37908-97-7 3,5-dichloro-4-methoxybenzoic acid 
• 4433-52-7 2,3-dihydro-benzothiazole 

Downstream Products

• 1285572-51-1 (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxo-1,2-dihydro-3H-1λ⁶-1,3-benzothiazol-3-yl)methanone 

Relevant academic research and scientific papers

Preparation method of dotinurad

The invention discloses a preparation method of dotinurad. According to the preparation method, condensation, cyclization, oxidation and other reactions are conducted in sequence, with 2-aminobenzenemercaptan used as an initial raw material, so the target product dotinurad is obtained. The preparation method has the advantages of easily available raw materials, rapidness, convenience, economic performance, environmental protection performance and suitability for large-scale industrial production.

Preparation method of dotinurad

The invention discloses a preparation method of dotinurad. The preparation method comprises the following steps: with 2-aminophenylmercaptan as an initial raw material, sequentially carrying out acylation, cyclization of diiodomethane, oxidation and other reactions to obtain the target product dotinurad. The preparation method has the advantages of easily available raw materials, rapidness, convenience, economic performance and environmental protection performance, overcomes the use of formaldehyde in existing processes, and is suitable for large-scale industrial production.

NOVEL PHENOL DERIVATIVE

Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt t