1285573-35-4Relevant academic research and scientific papers
Synthesis of isoxazoles by hypervalent iodine-induced cycloaddition of nitrile oxides to alkynes
Jawalekar, Anup M.,Reubsaet, Erik,Rutjes, Floris P. J. T.,Van Delft, Floris L.
, p. 3198 - 3200 (2011/05/05)
Treatment of oximes with hypervalent iodine leads to substituted isoxazoles via rapid formation of nitrile oxides. Reaction with terminal alkynes led to a series of 3,5-disubstituted isoxazoles with complete regioselectivity and high yield, in a procedure
