1285694-91-8Relevant academic research and scientific papers
Ammonium iodide-promoted cyclization of ketones with DMSO and ammonium acetate for synthesis of substituted pyridines
Pan, Xiaojun,Liu, Qiao,Chang, Liming,Yuan, Gaoqing
, p. 51183 - 51187 (2015)
A simple and efficient method has been developed for the synthesis of symmetrical and unsymmetrical pyridines via NH4I-promoted cyclization of ketones with DMSO and NH4OAc. It was found that methyl ketones always gave selective forma
Iron-Catalyzed Cyclization of Ketoxime Carboxylates and Tertiary Anilines for the Synthesis of Pyridines
Zhao, Mi-Na,Ren, Zhi-Hui,Yu, Le,Wang, Yao-Yu,Guan, Zheng-Hui
, p. 1194 - 1197 (2016/03/15)
A novel and efficient iron-catalyzed cyclization of ketoxime carboxylates and N,N-dialkylanilines for the modular synthesis of diverse pyridines was developed. The reaction was initiated by Fe-catalyzed N-O bond cleavage of ketoxime carboxylates in the presence of tertiary anilines. The methylene carbon on N,N-dialkylanilines functioned as a source of one-carbon synthon in the reaction. The reaction used readily available starting materials, tolerated various functional groups, and afforded 2,4-disubstituted and 2,4,6-trisubstituted pyridines in good to high yields under mild conditions.
Simple selective synthesis of 2,4- and 2,6-diarylpyridines through metal-free cyclocondensation of aromatic ketones with ammonium acetate
Liu, Jin,Wang, Chuanxin,Wu, Liansheng,Liang, Fen,Huang, Guosheng
experimental part, p. 4228 - 4234 (2011/02/22)
A simple and selective one-pot synthesis of 2,4- and 2,6-diarylpyridines through the cyclocondensation reaction of aromatic ketones with ammonium acetate has been developed. The procedure is metal-free, convenient, and efficient, and the substrates are re
