1285712-73-3Relevant academic research and scientific papers
Solvent-Controlled Chemoselectivity in the Photolytic Release of Hydroxamic Acids and Carboxamides from Solid Support
Qvortrup, Katrine,Petersen, Rico G.,Dohn, Asmus O.,M?ller, Klaus B.,Nielsen, Thomas E.
, p. 3263 - 3266 (2017)
The synthetic utility and theoretical basis of a photolabile hydroxylamine-linker are presented. The developed protocols enable the efficient synthesis and chemoselective photolytic release of either hydroxamates or carboxamides from solid support. The bi
METHOD OF TREATMENT AND DEVICE
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, (2020/07/25)
A method and an angioplasty balloon catheter used in a method of preventing or minimizing incidence of neointimal hyperplasia (NIH) in a blood vessel of an animal following angioplasty treatment. The method comprising locating the angioplasty balloon cath
Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor
Dear, Anthony E.,Liu, Hongbin,Mountford, Simon,Robinson, Andrea,Sama, Gopal R.,Thompson, Phillip
, (2020/06/05)
Hydroxamic acid-based histone deacetylase inhibitors (HDACi) are a class of epigenetic agents with potentially broad therapeutic application to several disease states including post angioplasty mediated neointimal hyperplasia (NIH). Precise spatiotemporal
A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES
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, (2015/03/28)
The photolabile hydrazine linker of the present invention is based on the o-nitro-veratryl group, which is capable of releasing hydrazide derivatives upon UV irradiation. The linker allows for a new solid-phase peptide synthesis (SPPS) strategy which is f
A photolabile linker for the solid-phase synthesis of peptide hydrazides and heterocycles
Qvortrup, Katrine,Komnatnyy, Vitaly V.,Nielsen, Thomas E.
, p. 4782 - 4785 (2015/04/27)
A photolabile hydrazine linker for the solid-phase synthesis of peptide hydrazides and hydrazine-derived heterocycles is presented. The developed protocols enable the efficient synthesis of structurally diverse peptide hydrazides derived from the standard
A photolabile linker for the solid-phase synthesis of 4-substituted NH-1,2,3-triazoles
Qvortrup, Katrine,Nielsen, Thomas E.
, p. 3278 - 3280 (2011/05/07)
This communication presents the synthesis of a novel photolabile azidolinker based on the o-nitroveratryl group. The application of this linker for the synthesis and photolytic release of NH-1,2,3-triazoles is described.
