128581-23-7Relevant academic research and scientific papers
On a chemoenzymatic desymmetrization-ring expansion strategy towards functionalized N-heterocycles
Thiel, Daniel,Deska, Jan
supporting information, p. 1529 - 1532 (2013/08/23)
The direct combination of the desymmetrization of N-heterocyclic meso-diols using lipase from Mucor miehei as biocatalyst and subsequent ring expansion of the optically active products by activation of the remaining hydroxy group gives rise to functionalized nonsymmetrical piperidines in a highly enantio- and dia stereoselective manner. Georg Thieme Verlag Stuttgart. New York.
THE IMINE-EPOXIDE REARRANGEMENT IN THE FORMATION OF TRANS-2,6-DISUBSTITUTED PIPERIDINES. A STEREOSELECTIVE SYNTHESIS OF (+/-)-TENERAIC ACID.
Wasserman, Harry H.,Rodriques, Karen,Kucharczyk, Roman
, p. 6077 - 6080 (2007/10/02)
Teneraic acid, a naturally-occurring trans-2,6-piperidine dicarboxylic acid, has been synthesized using the imine-epoxide rearrangement.
