128599-33-7

Basic information

• Product Name: 5-Hexyn-1-ol, 6-(4-methoxyphenyl)-
• CAS NO: 128599-33-7
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Mol File: 128599-33-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 5-Hexyn-1-ol, 6-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexyn-1-ol, 6-(4-methoxyphenyl)-(128599-33-7)
• EPA Substance Registry System: 5-Hexyn-1-ol, 6-(4-methoxyphenyl)-(128599-33-7)

Safety Data

• Hazardous Substances Data: 128599-33-7(Hazardous Substances Data)

Upstream product

• 83067-20-3 5-(tert-butyldimethyl-silyloxy)pentan-1-ol 
• 111-29-5 1 ,5-pentanediol 
• 928-90-5 5-hexyl-1-ol 
• 100-66-3 methoxybenzene 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 92078-68-7 1-(6-bromohex-1-yn-1-yl)-4-methoxybenzene 
• 1450663-59-8 1-(6-azidohex-1-yn-1-yl)-4-methoxybenzene 
• 856120-88-2 6-(4-methoxyphenyl)-5-hexyn-1-amine 
• 1299304-45-2 (Z)-6-(4-methoxyphenyl)hex-5-en-1-ol 
• 128578-11-0 3-{3-(2-Carboxy-ethyl)-4-[(Z)-6-(4-methoxy-phenyl)-hex-5-enyloxy]-benzoyl}-benzoic acid 
• 128577-87-7 2-{[6-(4-Methoxyphenyl)-5-hexynyl]oxy}-5-[3-(ethoxycarbonyl)benzoyl]benzenepropanoic acid ethyl ester 
• 128578-12-1 2-{[6-(4-Methoxyphenyl)-5-hexynyl]oxy}-5-(3-carboxybenzoyl)benzenepropanoic acid 
• 856439-43-5 6-(4-methoxyphenyl)hexanal 
• 805240-60-2 6-hydroxy-1-(4-methoxyphenyl)hexan-1-one 
• 128577-60-6 (5E)-6-(4-Methoxyphenyl)-5-hexen-1-ol 

Relevant articles and documents

Synthesis of Tetrasubstituted Alkenes by Tandem Metallacycle Formation/Cross-Electrophile Coupling

Nickel-catalyzed cross-electrophile couplings have recently emerged as highly effective and practical methods for the formation of C-C bonds. By merging this process with well-established π-π coupling chemistry, a new method for the synthesis of tetrasubstituted alkenes has been developed. The procedure relies on the use of chlorosilanes as a means of generating reactive vinylnickel intermediates, which are capable of undergoing a reductive cross-electrophile coupling with alkyl halides. The method not only generates highly substituted allylic alcohol derivatives but also obviates the need for stoichiometric organometallic nucleophiles and provides greatly improved scope and functional group tolerance compared with previously developed methods.

GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE

The present invention discloses a glycoside compound represented by Formula III, and a preparation method, a composition, use and an intermediate thereof. The glycoside compound provided in the present invention has simple preparation method, can significantly increase the expression of VEGF-A mRNA, and is effective in promoting the angiogenesis. This provides a reliable guarantee for the development of drugs with pro-angiogenic activity for treating cerebral infarction cerebral stroke, myocardial infarction, and ischemic microcirculatory disturbance of lower limbs.

Acid-Promoted Cascade Cyclization to Produce 2-(4′-Alkoxyaryl)-3,4-Fused Tricyclic Dihydrobenzopyrans via a Vinylidene para-Quinone Methide Intermediate

We developed a novel method for synthesizing 2-(4-hydroxyaryl)-3,4-fused tricyclic dihydrobenzopyrans with 2,3-syn and 3,4-syn motif based on the acid-promoted cascade cyclization via vinylidene para-quinone methide intermediates. Using easily prepared li