1286164-81-5Relevant articles and documents
The active carbon nano copper catalyst catalytic synthesis of 1, 2, 3 - triazole class is the compound of the method
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Paragraph 0055-0057, (2018/05/24)
The invention discloses a method for preparing a 1,2,3-triazoie compound through an active-carbon-carried nano-copper catalyst in a catalyzed synthesis mode, and belongs to the field of 1,2,3-triazoie compound synthesis technologies. According to the tech
'Click' ligand for 'click' chemistry: (1-(4-methoxybenzyl)-1-H-1,2,3-triazol-4-yl)methanol (MBHTM) accelerated copper-catalyzed [3+2] azide-alkyne cycloaddition (CuAAC) at low catalyst loading
Tale, Rajesh H.,Gopula, Venkatesh B.,Toradmal, Gopal K.
, p. 5864 - 5869 (2015/11/02)
Readily accessible, cost effective, remarkably stable and easily tunable 1,2,3-triazole based ligand, (1-(4-methoxybenzyl)-1-H-1,2,3-triazol-4-yl)methanol (MBHTM) synthesized itself by 'click' chemistry shown to promote the dramatic rate enhancement of co
Metallic copper wire: a simple, clear and reusable catalyst for the CuAAC reaction in supercritical carbon dioxide
Jiang, Yuqin,He, Xing,Zhang, Weiwei,Li, Xingfeng,Guo, Niu,Zhao, Yaru,Xu, Guiqing,Li, Wei
, p. 73340 - 73345 (2015/09/15)
An efficient protocol for the CuAAC reaction catalyzed by metallic copper wire for the synthesis of 1,4-disubstituted triazoles has been developed in supercritical carbon dioxide (scCO2) at 50 °C. The protocol could afford the corresponding pro
Lanthanum loaded CuO nanoparticles: synthesis and characterization of a recyclable catalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles and propargylamines
Sasikala,Rani, S. Kutti,Easwaramoorthy,Karthikeyan
, p. 56507 - 56517 (2015/07/15)
Lanthanum loaded CuO (LCO) nanoparticles (NPs) were successfully synthesized by a precipitation-thermal decomposition method and characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive spectra (EDS), diffuse reflectance spectra (DRS), photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and BET surface area measurements. The synthesized LCO NPs were used as a nanocatalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles by a click reaction of substituted benzyl azides and alkynes and the synthesis of propargylamines via three-component coupling reactions of aldehydes, alkynes and amines under ultrasonication. The one-pot operation, atom-economical nature, regioselectivity and good yields are the noteworthy features of this protocol. The reusability of the prepared nanocatalyst was successfully examined six times without any appreciable loss in catalytic activity.
Carboxymethylpullulan promoted Cu2O-catalyzed Huisgen-click reaction
Zhang, Weiwei,Ren, Baoqi,Jiang, Yuqin,Hu, Zhiguo
, p. 12043 - 12047 (2015/02/19)
A combination of carboxymethylpullulan (CMP) and Cu2O has been developed as a highly efficient catalytic system for the Huisgen-click reaction. Our results indicate that the acidic CMP could be used for 6 cycles without decreasing the activatin
A simple, efficient thermally promoted protocol for Huisgen-click reaction catalyzed by CuSO4·5H2O in water
Jiang, Yuqin,Kong, Duanyang,Zhao, Jinglin,Zhang, Weiwei,Xu, Wenjing,Li, Wei,Xu, Guiqing
supporting information, p. 2410 - 2414 (2014/05/06)
A thermally promoted and CuSO4-catalyzed new version of the Huisgen-click reaction is presented in this Letter. Notably, this protocol was suitable not only for the reactions between organic azides and alkynes, but also for one-pot three-component reactions among alkyl halides, NaN3, and alkynes.
Cu(OAc)2·H2O/NH2NH 2·H2O: An efficient catalyst system that in situ generates Cu2O nanoparticles and HOAc for Huisgen click reactions
Jiang, Yuqin,Kong, Duanyang,Zhao, Jinglin,Qi, Qinghua,Li, Wei,Xu, Guiqing
, p. 1010 - 1014 (2014/01/06)
A combination of Cu(OAc)2·H2O and NH 2NH2·H2O, which in situ generates Cu2O-NPs and HOAc in water at room temperature, has been developed as a highly efficient catalytic system for Huisgen
THERAPEUTICALLY ACTIVE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER CHARACTERIZED AS HAVING AN IDH MUTATION
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, (2011/06/26)
Compounds and compositions comprising compounds useful in the treatment of cancer are described herein. The compounds and compositions can be used to modulate an isocitrate dehydrogenase (IDH) mutant (e.g., IDHIm or IDH2m) having alpha hydroxyl neoactivity
An efficient ultrasound-assisted method for the synthesis of 1,4-Disubstituted triazoles
Jiang, Yuqin,Chen, Xiaolan,Qu, Lingbo,Wang, Junliang,Yuan, Jinwei,Chen, Senshen,Li, Xu
experimental part, p. 77 - 82 (2011/06/09)
An efficient method for the synthesis of 1,4-disubstituted triazoles has been developed with the help of ultrasound irradiation in water at room temperature. Under the optimized conditions, a novel series of 1,4-disubstituted 1,2,3-triazoles was synthesiz
