17061-85-7Relevant articles and documents
Polymer nanocomposites using click chemistry: Novel materials for hydrogen peroxide vapor sensors
Mazumdar, Payal,Rattan, Sunita,Mukherjee, Monalisa
, p. 69573 - 69582 (2015)
Herein, we report the synthesis of nanocomposites (NCs) prepared by azide-functionalized polystyrene (Az-f-PS) coupled with alkyne-functionalized nanographite platelets (Alk-f-NGPs) by using copper(i) catalyzed azide-alkyne click chemistry. Linear polysty
PREPARATION, CRYSTAL STRUCTURE AND DIELECTRIC PROPERTIES OF THE NEW UNSYMMETRICALLY SUBSTITUTED DIACETYLENES NP/R2.
Strohriegl,Schultes,Heindl,Gruner-Bauer,Enkelmann,Dormann
, p. 918 - 924 (1987)
We report on the preparation, the crystal structure and the dielectric properties of several new unsymmetrically substituted diacetylenes R//1 minus C EQUVLNT C-C EQUVLNT C-R//2 of the general constitution NP/R//2. They carry a polar nitrophenoxy-group on
New phenoxymethyl substituted mesoionic triazolium salts: Synthesis and structural characterisation
Dhimba, George,Lawal, Nasir S.,Bala, Muhammad D.
, p. 100 - 107 (2019)
A new set of mesoionic 1,2,3-triazolium salts functionalised by para substituted phenoxymethyl side groups were prepared using the ‘click’ Cu catalyzed [3 + 2] cycloaddition of organic azides and terminal alkynes. Four previously unreported neutral triazoles (1–4) were first isolated en route to formation of the salts (5–8). All the compounds were fully characterised (1H, 13C NMR; IR; HR-MS; EA) and representative neutral triazoles and salts were structurally characterised by single crystal X-ray diffraction (SCXRD). Full examination of structural characteristics of the neutral compounds and the salts were presented by detailed analysis of multinuclear NMR data and SCXRD. As metal-free catalysts for the transfer hydrogenation of ketones to alcohols in isopropanol as solvent and hydrogen source, salts 5–8 showed moderate activities for the transformation of acetophenone to 1-phenyl alcohol.
Functionalization of single-walled carbon nanotubes with well-defined polystyrene by "click" coupling
Li, Huaming,Cheng, Fuyong,Duft, Andy M.,Adronov, Alex
, p. 14518 - 14524 (2005)
Covalent functionalization of alkyne-decorated SWNTs with well-defined, azide-terminated polystyrene polymers was accomplished by the Cu(I)-catalyzed [3 + 2] Huisgen cycloaddition. This reaction was found to be extremely efficient in producing organosolub
Four-component, one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles bearing 1-(2-phenylselenocyclohexyl) group
Sheng, Wusheng,Sheng, Shouri,Zeng, Jiangbo,Huang, Zhenzhong,Cai, Mingzhong
, p. E222-E226 (2014)
An efficient, one-pot, three-step, regioselective synthesis of 4-substituted 1-(2-phenylselenocyclohexyl)-1,2,3-triazoles, involving in situ generation of l-azido-2-phenylselenocyclohexane has been developed via four-component reaction of phenylselenenyl
Synthesis of sorafenib analogues incorporating a 1,2,3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines
Palakhachane, Sarinya,Ketkaew, Yuwaporn,Chuaypen, Natthaya,Sirirak, Jitnapa,Boonsombat, Jutatip,Ruchirawat, Somsak,Tangkijvanich, Pisit,Suksamrarn, Apichart,Limpachayaporn, Panupun
supporting information, (2021/04/15)
A series of 1,2,3-triazole-containing Sorafenib analogues, in which the aryl urea moiety of Sorafenib (1) was replaced with a 1,2,3-triazole ring linking a substituted phenoxy fragment, were prepared successfully via Huisgen 1,3-dipolar cycloaddition and
Preparation method and application of propyne aryl ether compound
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Paragraph 0073-0074, (2021/08/28)
The invention particularly relates to a method for preparing propyne aryl ether compounds from aryl phenol, halogenated propyne and derivatives of the halogenated propyne, and belongs to the technical field of preparation of the propyne aryl ether compoun
COMPOUNDS AND METHOD FOR TREATING CYTOKINE RELEASE SYNDROME
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Page/Page column 108, (2021/02/12)
Disclosed herein are embodiments of a method for treating or preventing cytokine release syndrome (CRS). In certain embodiments, the method comprises administering a compound, or a salt, solvate, prodrug or pharmaceutical composition thereof, to a subject experiencing, or at risk of developing, CRS. The compound may be a kinase inhibitor, such as a JAK inhibitor and/or an IRAK inhibitor, and/or the compound may have a structure according to Formulas I, III, IV or VII. And the method may comprise administering the compound to a subject who is has received, is currently receiving, and/or will be receiving a cell therapy.
Azoacetylenes for the Synthesis of Arylazotriazole Photoswitches
Anderl, Felix,Balkenhohl, Moritz,Carreira, Erick M.,Fink, Moritz,Pfaff, Patrick
supporting information, p. 14495 - 14501 (2021/09/18)
We report a modular approach toward novel arylazotriazole photoswitches and their photophysical characterization. Addition of lithiated TIPS-acetylene to aryldiazonium tetrafluoroborate salts gives a wide range of azoacetylenes, constituting an underexplored class of stable intermediates.In situdesilylation transiently leads to terminal arylazoacetylenes that undergo copper-catalyzed cycloadditions (CuAAC) with a diverse collection of organoazides. These include complex molecules derived from natural products or drugs, such as colchicine, taxol, tamiflu, and arachidonic acid. The arylazotriazoles display near-quantitative photoisomerization and long thermalZ-half-lives. Using the method, we introduce for the first time the design and synthesis of a diacetylene platform. It permits implementation of consecutive and diversity-oriented approaches linking two different conjugants to independently addressable acetylenes within a common photoswitchable azotriazole. This is showcased in the synthesis of several photoswitchable conjugates, with potential applications as photoPROTACs and biotin conjugates.
Novel ferrocene-based 1,2,3-triazolyl compounds: Synthesis, anti-migration properties and catalytic effects on oxidizers during combustion
Cheng, Wenqian,Shi, Xiaoling,Zhang, Yu,Jian, Yajun,Zhang, Guofang
, (2019/12/26)
To tackle high-migratory and high-volatility problem of marketed neutral ferrocene-based burning rate catalysts, twenty-one ferrocene-based 1,2,3-triazolyl compounds (Fc-TAZs) were synthesized by click reaction and characterized completely by NMR, FT-IR,
