1286188-96-2Relevant academic research and scientific papers
Total synthesis of the cytotoxic 1,10-seco-eudesmanolides britannilactone and 1,6-O,O-diacetylbritannilactone
Merten, Joern,Wang, Yuzhou,Krause, Tilo,Kataeva, Olga,Metz, Peter
, p. 3332 - 3334 (2011/04/26)
A natural boost! The first synthetic access to the bioactive title compounds was achieved from the dienyl carboxylic acid 1 (see scheme), which in turn is readily available by using sultone chemistry. The enantioselective route developed here also confirms the relative and absolute configuration of these sesquiterpene lactones. Copyright
