1286716-15-1

Basic information

• Product Name: ethyl 6-bromo-7-((dimethylamino)methyl)-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate
• Synonyms: ethyl 6-bromo-7-((dimethylamino)methyl)-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate
• CAS NO: 1286716-15-1
• Molecular Weight: 482.373
• Mol File: 1286716-15-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 6-bromo-7-((dimethylamino)methyl)-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-bromo-7-((dimethylamino)methyl)-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate(1286716-15-1)
• EPA Substance Registry System: ethyl 6-bromo-7-((dimethylamino)methyl)-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate(1286716-15-1)

Safety Data

• Hazardous Substances Data: 1286716-15-1(Hazardous Substances Data)

Upstream product

• 88-00-6 ethyl 2,4-dichloro-3-oxobutanoate 
• 39903-01-0 2-amino-3-hydroxy-5-bromopyridine 
• 24016-03-3 2-amino-3-benzyloxypyridine 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 1286716-32-2 ethyl 6-bromo-2-(chloromethyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate 
• 50-00-0 formaldehyd 
• 1286716-36-6 ethyl 6-bromo-2-((4-fluorophenylthio)methyl)-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate 
• 124-40-3 dimethyl amine 
• 754230-78-9 3-(benzyloxy)-5-bromopyridine-2-amine 
• 16867-03-1 2-amino-3-hydroxypyridine 

Relevant articles and documents

Synthesis and in-vitro anti-hepatitis B virus activity of ethyl 6-Bromo-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylates

A series of ethyl 6-bromo-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate derivatives were synthesized and evaluated for their anti-hepatitis B virus (HBV) activity and cytotoxicity in HepG2.2.15 cells. Nearly half of the tested compounds were proved to be highly effective in inhibiting the replication of HBV DNA with IC50 values ranging from 1.3 to 9.1 μM. Among them, 10o and 10s were identified as the most promising compounds.