128677-93-0

Upstream product

• 143251-56-3 (S)-4-Benzyl-3-((2R,3S)-2-bromo-3-phenyl-butyryl)-oxazolidin-2-one 
• 128677-86-1 C₁₅H₂₀O₃ 
• 128677-88-3 (4S)-N-[(3R)-phenylbutanoyl]-4-phenylmethyl-1,3-oxazolidin-2-one 
• 772-14-5 (R)-3-phenylbutyric acid 
• 148706-31-4 (S)-3-((2S,3S)-2-Bromo-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 
• 146137-33-9 (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one 
• 4593-90-2 3-phenylbutyric acid 
• 160636-94-2 (S)-3-((2R,3S)-2-Azido-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 
• 128707-89-1 (4R)-3-(2'S,3'S)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128707-87-9 (4S)-3-(2'R,3'S)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128677-91-8 (4S)-3-(2'R,3'R)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128677-90-7 (4R)-3-(3'R)-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128677-89-4 (R)-4-Benzyl-3-((S)-3-phenyl-butyryl)-oxazolidin-2-one 
• 128677-85-0 C₁₅H₂₀O₃ 

Downstream Products

• 59905-30-5 threo-D-(2R,3S)-β-methylphenylalanine 
• 25488-25-9 (2S,3S)-methylphenylalanine 

Relevant academic research and scientific papers

AMINO ACID DERIVATIVE

The present invention relates to an amino acid derivative having an angiotensin I-converting enzyme inhibition activity, a vasopressin antagonism and an atrial natriuretic peptide hydrolase inhibition activity.This amino acid derivative is represented by the following general formula (I): STR1 wherein R 1 represents a hydrogen atom or an acyl group; R 2 represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, an ary group which may have a substituent, a heteroaryl group which may have a substituent, an arylalkyl group which may have a substituent or a heteroarylalkyl group which may have a substituent;m and n represent each independently an integer of 0, 1 or 2 and J represents a cyclic group having an angiotensin I-converting enzyme inhibition activity.

A new strategy for the synthesis of four individual isomers of β-methylphenylalanine

The application of an allylic strain effect in boron enolates and asymmetric Michael-like addition/electrophilic bromination reactions is reported for the asymmetric synthesis of the individual isomers of unusual constrained amino acids. For β-substituted

Exploration for Large-scale Stereoselective Synthesis of Unusual Amino Acids by using 4-Phenyoxazolidin-2-one as a New Chiral Resolution Reagent

Individual isomers of β-branched α-amino acids have been stereoselectively and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

Asymmetric synthesis of unusual amino acids: An efficient synthesis of optically pure isomers of β-methylphenylalanine

Substitution of the diastereotopic β-hydrogens of many α-amino acids provides an approach to the three dimensional topographic control of peptide structure. Asymmetric synthesis of the desired amino acids is needed to facilitate these studies. All four in

ASYMMETRIC SYNTHESIS OF UNUSUAL AMINO ACIDS: SYNTHESIS OF OPTICALLY PURE ISOMERS OF β-METHYLPHENYLALANINE

All the four individual isomers of β-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers.