25488-25-9

Basic information

• Product Name: (2S,3S)-methylphenylalanine
• Synonyms: (2S,3S)-methylphenylalanine
• CAS NO: 25488-25-9
• Molecular Weight: 179.219
• Mol File: 25488-25-9.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: (2S,3S)-methylphenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-methylphenylalanine(25488-25-9)
• EPA Substance Registry System: (2S,3S)-methylphenylalanine(25488-25-9)

Safety Data

• Hazardous Substances Data: 25488-25-9(Hazardous Substances Data)

Upstream product

• 119838-28-7 (2S,5S,1'S)-2-t-butyl-1-t-butyloxycarbonyl-3-methyl-5-(1-methyl-benzyl)-4-imidazolidinone 
• 85146-09-4 AK-toxin I 
• 1449299-79-9 C₂₇H₂₁N₃O₃ 
• 908129-34-0 (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide 
• 1449299-96-0 C₂₄H₂₅N₅O₃ 
• 1449299-94-8 C₁₉H₁₇N₅O 
• 585-71-7 (1-bromoethyl)benzne 
• 128677-91-8 (4S)-3-(2'R,3'R)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128677-89-4 (R)-4-Benzyl-3-((S)-3-phenyl-butyryl)-oxazolidin-2-one 
• 128677-85-0 C₁₅H₂₀O₃ 
• 128677-88-3 (4S)-N-[(3R)-phenylbutanoyl]-4-phenylmethyl-1,3-oxazolidin-2-one 
• 128677-87-2 (4S)-N-[(3S)-phenylbutanoyl]-4-phenylmethyl-1,3-oxazolidin-2-one 
• 4593-90-2 (S)-2-phenylbutanoic acid 
• 143251-56-3 (R)-4-Benzyl-3-((2S,3S)-2-bromo-3-phenyl-butyryl)-oxazolidin-2-one 

Downstream Products

• 247175-69-5 N-(9-fluorenylmethoxycarbonyl)-(2S,3S)-erythro-L-β-methylphenylalanine 
• 90731-57-0 (βS)-N-(tert-butoxycarbonyl)-β-methyl-L-phenylalanine 
• 247175-70-8 methyl (8R,9S,2'S,3'S,2E,4Z,6E)-9,10-epoxy-8-[2'-(9-fluorenylmethylcarbamino)-3'-phenylbutanoyloxy]-9-methyl-2,4,6-decatrienoate 
• 247175-71-9 methyl (8R,9S,2'S,3'S,2E,4Z,6E)-8-[2'-amino-3'-phenylbutanoyloxy]-9,10-epoxy-9-methyl-2,4,6-decatrienoate 
• 25488-28-2 (2S,3S)-N-acetyl-β-methylphenylalanine 
• 128502-51-2 (S,S)-erythro-β-methyl-p-nitro-L-phenylalanine 
• 93-53-8 (S)-2-phenyl-propionaldehyde 

Relevant articles and documents

Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H Bonds with Primary Alkyl Halides

We report a new set of reactions based on the Pd-catalyzed alkylation of methylene C(sp3)-H bonds of aliphatic quinolyl carboxamides with α-haloacetate and methyl iodide and applications in the stereoselective synthesis of various β-alkylated α-amino acids. These reactions represent the first generally applicable method for the catalytic alkylation of unconstrained and unactivated methylene C-H bonds with high synthetic relevance. When applied with simple isotope-enriched reagents, they also provide a convenient and powerful means to site-selectively incorporate isotopes into the carbon scaffolds of amino acid compounds.

A Versatile Chemo-Enzymatic Route to Enantiomerically Pure β-Branched α-Amino Acids

A series of diastereoisomers of β-methyl-β-phenylalanine analogues 1a?f have been prepared in enantiomerically pure form using a combination of chemo- and biocatalysis. Starting from l-threonine methyl ester 2, a range of β,β-disubstituted didehydroamino

Catalytic asymmetric hydrogenation of α-(acetamido)acrylates using TRAP trans-chelating chiral bisphosphine ligands: Remarkable effects of ligand P-substituent and hydrogen pressure on enantioselectivity

The catalytic asymmetric hydrogenation of α-(acetamido)acrylates was carded out with the rhodium complexes prepared from [Rh(cod)2]BF4 and trans-chelating chiral bisphosphine ligands, (S,S)-2,2'-bis[(R)-1-(dialkylphosphino)ethyl]-1,1