128707-87-9

Upstream product

• 128677-90-7 (4R)-3-(3'R)-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 143251-56-3 (S)-4-Benzyl-3-((2R,3S)-2-bromo-3-phenyl-butyryl)-oxazolidin-2-one 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 372504-89-7 (R)-4-benzyl-2-oxazolidinone lithium salt 
• 4593-90-2 (S)-2-phenylbutanoic acid 
• 128677-88-3 (4S)-N-[(3R)-phenylbutanoyl]-4-phenylmethyl-1,3-oxazolidin-2-one 
• 101711-90-4 (S)-4-benzyl-2-oxazolidinone lithium salt 
• 128677-86-1 C₁₅H₂₀O₃ 
• 772-14-5 (R)-3-phenylbutyric acid 

Downstream Products

• 59905-30-5 threo-D-(2R,3S)-β-methylphenylalanine 
• 128677-93-0 (2R)-azido-(3S)-phenylbutanoic acid 

Relevant academic research and scientific papers

AMINO ACID DERIVATIVE

The present invention relates to an amino acid derivative having an angiotensin I-converting enzyme inhibition activity, a vasopressin antagonism and an atrial natriuretic peptide hydrolase inhibition activity.This amino acid derivative is represented by the following general formula (I): STR1 wherein R 1 represents a hydrogen atom or an acyl group; R 2 represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, an ary group which may have a substituent, a heteroaryl group which may have a substituent, an arylalkyl group which may have a substituent or a heteroarylalkyl group which may have a substituent;m and n represent each independently an integer of 0, 1 or 2 and J represents a cyclic group having an angiotensin I-converting enzyme inhibition activity.

Asymmetric synthesis of unusual amino acids: An efficient synthesis of optically pure isomers of β-methylphenylalanine

Substitution of the diastereotopic β-hydrogens of many α-amino acids provides an approach to the three dimensional topographic control of peptide structure. Asymmetric synthesis of the desired amino acids is needed to facilitate these studies. All four in

ASYMMETRIC SYNTHESIS OF UNUSUAL AMINO ACIDS: SYNTHESIS OF OPTICALLY PURE ISOMERS OF β-METHYLPHENYLALANINE

All the four individual isomers of β-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers.