128720-23-0Relevant academic research and scientific papers
An efficient transformation of ethers to N,N′-disubstituted ureas in a Ritter type reaction
Panduranga, Veladi,Basavaprabhu,Sureshbabu, Vommina V.
, p. 975 - 979 (2013/04/10)
A simple, mild, and an alternative protocol for the preparation of N,N′-disubstituted ureas from readily available ethers and cyanamides as starting materials is described. The protocol explores the reactivity of ether in a Ritter type reaction with cyanamide in the presence of BF 3·Et2O and resulting in the formation of N,N′-disubstituted urea. Divinyl ether as well as MTBE (methyl tert-butyl ether) can be employed as ether components to afford allyl and tert-butyl ureas respectively.
Iron(III) catalysed synthesis of unsymmetrical di and trisubstituted ureas - A variation of classical Ritter reaction
Basavaprabhu, Hosamani,Sureshbabu, Vommina V.
supporting information; experimental part, p. 2528 - 2533 (2012/04/23)
An application of the classical Ritter reaction for the synthesis of unsymmetrical di and trisubstituted ureas catalyzed by FeCl3 is described. The protocol is of significant interest in view of the easy availability of precursors, mild reaction conditions employed and interestingly its applicability for the alkylation of alcohols capable of forming stable carbocationic intermediates even to the sterically hindered moieties. The Royal Society of Chemistry 2012.
Enzymatic Oxidative Conversion of Thio to Oxo by Baker's Yeast in Thiocarbamates and Thioureas
Kamal, Ahmed,Rao, Maddamsetty V.,Rao, Adari B.
, p. 655 - 656 (2007/10/02)
The enzymatic conversion of aryl allylthiocarbamates and 1-allyl-3-arylthioureas by baker's yeast to the corresponding carbamates and ureas in good yields is described.
