128735-68-2Relevant academic research and scientific papers
Asymmetric total synthesis from cyclopentene-1,2-diones: Characterisation of a diastereomerically pure Michael adduct
Brown,Ford
, p. 2029 - 2032 (2007/10/02)
A key cyclopentenolone intermediate in the asymmetric synthesis of alkaloids and seco-iridoids has been prepared from reaction of a chiral 5,7-dioxoperhydro-1,4-oxazepine with a cyclopentene-1,2-dione dimer; the absolute configuration at the induced chiral centres has been assigned from n.O.e. experiments.
Asymmetric total synthesis of alkaloids and seco-iridoids
Brown, Richard T.,Ford, Mark J.
, p. 2033 - 2036 (2007/10/02)
A chiral cyclopentenolone from Michael addition of an oxazepine derived from ephedrine to a cyclopentene-1,2-dione has been converted into pure enantiomers of established synthetic precursors to alkaloids and seco-iridoids via a novel exchange which recov
