67376-72-1

Basic information

• Product Name: (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE)
• Synonyms: (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE)
• CAS NO: 67376-72-1
• Molecular Formula: C₁₃H₁₅NO₃
• Molecular Weight: 233.26
• Mol File: 67376-72-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 457.069°C at 760 mmHg
• Flash Point: 230.228°C
• Appearance: /
• Density: 1.146g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE)(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE)(67376-72-1)
• EPA Substance Registry System: (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE)(67376-72-1)

Safety Data

• Hazardous Substances Data: 67376-72-1(Hazardous Substances Data)

Usage

General Description

The chemical compound (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE is a stereoisomer of the oxazepine molecule. It has a molecular formula of C15H17NO3 and a molecular weight of 259.30 g/mol. (2R,3S)-(-)-3,4-DIMETHYL-5,7-DIOXO-2-PHENYLPERHYDRO-1,4-OXAZEPINE) is a cyclic organic compound containing a six-membered ring with oxygen and nitrogen atoms. It is often used in pharmaceutical research and development as a potential drug candidate due to its pharmacological properties. However, further studies and testing are necessary to determine its specific applications and potential therapeutic uses.

InChI:InChI=1/C13H15NO3/c1-9-13(10-6-4-3-5-7-10)17-12(16)8-11(15)14(9)2/h3-7,9,13H,8H2,1-2H3/t9-,13-/m0/s1

Upstream product

• 16695-14-0 Malonic acid monomethyl ester 
• 299-42-3 ephedrine 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 1237025-10-3 (2R,3S,Z)-6-(4-(3-bromobenzyloxy)benzylidene)-3,4-dimethyl-2-phenyl-1,4-oxazepane-5,7-dione 
• 69798-28-3 (E)-(2R,3S)-6-isobutylidene-3,4-dimethyl-2-phenylperhydro-1,4-oxazepine-5,7-dione 
• 123356-39-8 (2S,3S)-(Z)-isobutylidene-3,4-dimethyl-2-phenyl-[1,4]oxazepane-5,7-dione 
• 75291-15-5 (2S,3S)-(E)-butylidene-3,4-dimethyl-2-phenyl-[1,4]oxazepane-5,7-dione 
• 738627-95-7 (2S,3S)-(E)-(2,2-dimethylpropylidene)-3,4-dimethyl-2-phenyl-[1,4]oxazepane-5,7-dione 
• 738628-02-9 (2S,3S)-(Z)-(2,2-dimethylpropylidene)-3,4-dimethyl-2-phenyl-[1,4]oxazepane-5,7-dione 
• 161297-28-5 (2R,3S)-(-)-6-Diazo-3,4-dimethyl-2-phenyl-1,4-oxazepan-5,7-dion 
• 65092-79-7 (2R)-6-(Z)-benzylidene-3c,4-dimethyl-2r-phenyl-[1,4]oxazepane-5,7-dione 
• 65092-79-7 (2R,3S)-3,4-Dimethyl-2-phenyl-6-[1-phenyl-meth-(E)-ylidene]-[1,4]oxazepane-5,7-dione 
• 128735-66-0 (4R,5S)-5-((2R,3S,6S)-3,4-Dimethyl-5,7-dioxo-2-phenyl-[1,4]oxazepan-6-yl)-4-ethyl-2-hydroxy-3-oxo-cyclopent-1-enecarboxylic acid methyl ester 
• 98720-17-3 C₂₅H₂₇NO₄ 
• 98720-21-9 (2R,3S)-3,4-Dimethyl-6-[1-[2-(3-methyl-but-2-enyloxy)-phenyl]-meth-(Z)-ylidene]-2-phenyl-[1,4]oxazepane-5,7-dione 
• 98720-21-9 (2R,3S)-3,4-Dimethyl-6-[1-[2-(3-methyl-but-2-enyloxy)-phenyl]-meth-(E)-ylidene]-2-phenyl-[1,4]oxazepane-5,7-dione 
• 78844-15-2 (2R,3S)-3,4-Dimethyl-6-((R)-2-nitro-cyclohexyl)-2-phenyl-[1,4]oxazepane-5,7-dione 

Relevant articles and documents

Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation

Two asymmetric methods to synthesize a potent GPR40 receptor agonist are reported. Both synthetic routes utilize readily available, inexpensive starting materials and reagents. The first route relies on a highly diastereoselective conjugate alkynylation of an ephedrine-derived oxazepanedione acceptor. The second route features the enantioselective alkynylation of a Meldrum's acid-derived acceptor mediated by a chiral zinc cinchonidine reagent.

Hochenantioselektive intramolekulare Hetero-Diels-Alder-Reaktionen zur Synthese enantiomerenreiner tricyclischer Lactone

-