128735-66-0

Upstream product

• 91020-93-8 3a,6a-Diethyl-2,5-dihydroxy-3,6-dioxo-3,3a,3b,6,6a,6b-hexahydro-cyclobutadicyclopentene-1,4-dicarboxylic acid dimethyl ester 
• 67376-72-1 (2R,3S)-3,4-dimethyl-2-phenylperhydro-1,4-oxazepine-5,7-dione 
• 73494-16-3 (2S,3R)-3,4-Dimethyl-2-phenyl-1,4-oxazepan-5,7-dion 

Downstream Products

• 128735-68-2 (4R,5S)-5-((2R,3S,6S)-3,4-Dimethyl-5,7-dioxo-2-phenyl-[1,4]oxazepan-6-yl)-4-ethyl-2-methoxy-3-oxo-cyclopent-1-enecarboxylic acid methyl ester 
• 128735-69-3 (4R,5S)-5-{[((1S,2R)-2-Acetoxy-1-methyl-2-phenyl-ethyl)-methyl-carbamoyl]-methoxycarbonyl-methyl}-4-ethyl-2-methoxy-3-oxo-cyclopent-1-enecarboxylic acid methyl ester 
• 128735-67-1 (3R,4R,5S)-5-{[((1S,2R)-2-Acetoxy-1-methyl-2-phenyl-ethyl)-methyl-carbamoyl]-methoxycarbonyl-methyl}-4-ethyl-3-hydroxy-2-methoxy-cyclopent-1-enecarboxylic acid methyl ester 
• 130253-24-6 (3R,4R,5R)-3-Acetoxy-5-{[((1S,2R)-2-acetoxy-1-methyl-2-phenyl-ethyl)-methyl-carbamoyl]-methoxycarbonyl-methyl}-4-ethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 
• 130253-47-3 N-((1S,2R)-2-Acetoxy-1-methyl-2-phenyl-ethyl)-N-methyl-malonamic acid methyl ester 

Relevant academic research and scientific papers

Asymmetric total synthesis from cyclopentene-1,2-diones: Characterisation of a diastereomerically pure Michael adduct

A key cyclopentenolone intermediate in the asymmetric synthesis of alkaloids and seco-iridoids has been prepared from reaction of a chiral 5,7-dioxoperhydro-1,4-oxazepine with a cyclopentene-1,2-dione dimer; the absolute configuration at the induced chiral centres has been assigned from n.O.e. experiments.