128760-37-2

Upstream product

• 115104-50-2 3-[(2-Dimethylcarbamoyl-ethylsulfanyl)-(3-hydroxymethyl-phenyl)-methylsulfanyl]-propionic acid methyl ester 
• 52010-98-7 3-(hydroxymethyl)benzaldehyde 
• 115104-50-2 3-[(2-Dimethylcarbamoyl-ethylsulfanyl)-(3-hydroxymethyl-phenyl)-methylsulfanyl]-propionic acid methyl ester 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 115104-47-7 3-[[3-(tert-Butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 110130-71-7 3-(((tert-butyldiphenylsilyl)oxy)methyl)benzaldehyde 
• 626-19-7 Isophthalaldehyde 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 115104-47-7 3-[[3-(tert-Butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 124573-23-5 (R)-Methoxy-phenyl-thioacetic acid S-[(2-dimethylcarbamoyl-ethylsulfanyl)-(3-formyl-phenyl)-methyl] ester 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 115104-27-3 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 115104-28-4 (-)-L-660,711 
• 115104-27-3 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 115104-28-4 (+)-L-660,711 
• 120443-15-4 (+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate 
• 120385-96-8 dimethyl 5-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-4,6-dithianonanedioate 

Relevant academic research and scientific papers

Synthesis of chiral thioacetals and thioethers

Thioacids, thiols, an acid, and an aldehyde are used to produce chiral thioacetals of the general formula. STR1 The compounds are leukotriene antagonists.

2-substituted quinoline dioic acids and pharmaceutical compositions

Compounds having the formula: STR1 are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.

ASYMMETRIC DITHIOACETALS III: THE PREPARATION OF THE ENANTIOMERS OF 3-((((3-(2-(7-CHLOROQUINOLIN-2-YL)-(E)-ETHENYL)PHENYL)-3-DIMETHYLAMINO-3-OXOPROPYLTHIO)METHYL)THIO)PROPIONIC ACID (L-660,711) (MK-571), AN ANTAGONIST OF LEUKOTRIENE D4

The application of a novel method for the preparation of chiral dithioacetals to the synthesis of the enantiomers of L-660,711, an antagonist of leukotriene D4, is described.Reaction of 3-(t-butyldiphenylsilyloxymethyl)benzaldehyde or isophthal

2-Substituted quinoline dioic acids

Compounds having the formula: are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.