1287753-49-4

Basic information

• Product Name: (E)-2-oxo-2-phenylacetaldehyde O-trityl oxime
• Synonyms: (E)-2-oxo-2-phenylacetaldehyde O-trityl oxime
• CAS NO: 1287753-49-4
• Molecular Weight: 391.469
• Mol File: 1287753-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-oxo-2-phenylacetaldehyde O-trityl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-oxo-2-phenylacetaldehyde O-trityl oxime(1287753-49-4)
• EPA Substance Registry System: (E)-2-oxo-2-phenylacetaldehyde O-trityl oxime(1287753-49-4)

Safety Data

• Hazardous Substances Data: 1287753-49-4(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 532-54-7 E-isonitrosoacetophenone 
• 76-83-5 trityl chloride 

Downstream Products

• 56613-81-1 (S)-2-Amino-1-phenyl-1-ethanol 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 

Relevant articles and documents

Asymmetric reduction of α-keto aldoxime o -ethers

The catalytic asymmetric reduction of -keto aldoxime O-methyl, O-benzyl, and O-trityl ethers, derived from substituted acetophenones, with borane/oxazaborolidines, by transfer hydrogenation, and with yeast, was studied. The reduction with borane/oxazaborolidines produced the corresponding -hydroxy oxime ethers, -hydroxy hydroxylamine ethers, and -amino alcohols in 39-78% yields and up to 77% ee. The carbonyl group was selectively reduced by transfer hydrogenation with formic acid-triethylamine catalyzed by RhCl[(R,R)-TsDPEN](Ce, and also with yeast, producing -hydroxy oxime ethers, up to 75% ee and 93% ee, respectively. Georg Thieme Verlag Stuttgart New York.