128863-93-4

Upstream product

• 103-80-0 phenylacetyl chloride 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 128863-85-4 N-(2-methylprop-2-enyl)benzylamide 

Downstream Products

• 333956-68-6 (1R,5S)-5-methyl-1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one 
• 345350-11-0 (1R,2S)-1-phenyl-2-methyl-2-(hydroxymethyl)-N,N-diethylcyclopropanecarboxamide 
• 345350-13-2 (1R,2S)-1-phenyl-2-methyl-2-(azidomethyl)-N,N-diethylcyclopropanecarboxamide 
• 57496-93-2 5-methyl-1-phenyl-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 271246-25-4 ethyl 2-methylallyl 2-diazo-2-phenylacetate 

Relevant academic research and scientific papers

A New Enantioselective Synthesis of Milnacipran and an Analogue by Catalytic Asymmetric Cyclopropanation

Milnacipran and analogues are conveniently prepared by a short sequence of steps from phenylacetic acid, the key step being highly enantio-selective catalytic asymmetric cyclopropanation.

Dirhodium(II) tetrakis[methyl 2-oxaazetidine-4-carboxylate]: A chiral dirhodium(II) carboxamidate of exceptional reactivity and selectivity

A new chiral azetidinone-carboxylate ligand for dirhodium(II) catalysts enhances reactivity toward diazo decomposition and selectivity toward cyclopropanation enabling diazomalonates, vinyldiazoacetates, and aryldiazoacetates to be effectively used with a dirhodium(II) carboxamidate catalyst.

THE NITROGENATED ALLYLIC SYSTEM AS AN INTRAMOLECULAR NUCLEOPHILE: A NEW ROUTE TO PYRAZOLES

A new route to pyrazoles via the cyclization of N-allyl-N-nitrosoamides is described.