1289638-90-9Relevant academic research and scientific papers
Dialkylzinc-mediated allylic polyfluoroarylation reaction
Kurauchi, Daisuke,Hirano, Keiichi,Kato, Hisano,Saito, Tatsuo,Miyamoto, Kazunori,Uchiyama, Masanobu
, p. 5849 - 5857 (2015/08/03)
Abstract We present an allylic polyfluoroarylation reaction with broad substrate scope and excellent functional group tolerance, using organozinc reagents under mild conditions. A catalytic amount of triphenylphosphine oxide efficiently promotes iodine-zinc exchange reaction between polyfluoroaryl iodide and dimethylzinc, and the resulting phosphine oxide-activated polyfluoroarylzinc undergoes substitution reaction with allylic halides to afford the corresponding polyfluoroarylated products.
Regio- and stereoselective allylic C-H arylation with electron-deficient arenes by 1,1′-Bi-2-naphthol-palladium cooperation
Wang, Gang-Wei,Zhou, An-Xi,Li, Shi-Xia,Yang, Shang-Dong
supporting information, p. 3118 - 3121 (2014/06/23)
A palladium-catalyzed allylic C-H arylation reaction with electron-deficient arenes with high regio- and stereoselectivity is reported. This work represents the first successful use of 1,1′-bi-2-naphthol as the ancillary ligand in allylic C-H activation, which is the key factor for chemoselectivity. Furthermore, high selectivity allylic C-H acetoxylation and amination were also successfully achieved under the same catalytic system.
Palladium-catalyzed aerobic oxidative allylic C-H arylation of alkenes with polyfluorobenzenes
Jiang, Huanfeng,Yang, Wanfei,Chen, Huoji,Li, Jianxiao,Wu, Wanqing
, p. 7202 - 7204 (2014/07/07)
An aerobic oxidative cross-coupling reaction of alkenes with polyfluorobenzenes, through palladium-catalyzed allylic C-H activation, is reported. This attractive route provides a new way to forge allylic C-C bonds of valuable products, in good yields, with high regioselectivity.
Copper- and phosphine-ligand-free palladium-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides
Yu, Yan-Bo,Fan, Shilu,Zhang, Xingang
supporting information, p. 14643 - 14648 (2013/01/15)
Simply id(all)ylic: A copper- and phosphine-ligand-free Pd-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides and the reaction mechanism are described (see scheme). The simple catalytic system, broad substrate scope,
Direct palladium-catalyzed intermolecular allylation of highly electron-deficient polyfluoroarenes
Fan, Shilu,Chen, Fei,Zhang, Xingang
, p. 5918 - 5923 (2011/08/02)
A simple operation: The use of readily available PPh3, high reaction efficiency, and good stereo- and regioselectivity provided useful and operationally simple access to polyfluoroarylated derivatives through the title transformation (see schem
Stereospecific copper-catalyzed C-H allylation of electron-deficient arenes with allyl phosphates
Yao, Tomoyuki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 2990 - 2994 (2011/04/23)
(Chemical Equation Presented) Rapid and concise: The title reaction proceeds via copper complexes in a highly stereospecific manner (see scheme; acac=acetylacetonate, phen=1,10-phenanthroline, TBS=tBuMe2Si). The catalysis provides a rapid and c
