1289675-16-6

Basic information

• Product Name: 1-methyl-3-butylimidazolium ibuprofenate
• Synonyms: 1-methyl-3-butylimidazolium ibuprofenate
• CAS NO: 1289675-16-6
• Molecular Weight: 344.497
• Mol File: 1289675-16-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-butylimidazolium ibuprofenate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-butylimidazolium ibuprofenate(1289675-16-6)
• EPA Substance Registry System: 1-methyl-3-butylimidazolium ibuprofenate(1289675-16-6)

Safety Data

• Hazardous Substances Data: 1289675-16-6(Hazardous Substances Data)

Upstream product

• 15687-27-1 ibuprofen 
• 65039-05-6 1-methyl-3-(n-butyl)imidazolium iodide 
• 366491-15-8 1-butyl-3-methyl-1H-imidazol-3-iumhydrogencarbonate 
• 79917-90-1 1-butyl-3-methylimidazolium chloride 
• 31121-93-4 sodium 2-(4-isobutylphenyl)propionate 

Relevant articles and documents

Effect of 1-Butyl-3-methylimidazolium Ibuprofenate as an Active Pharmaceutical Ingredient Ionic Liquid (API-IL) on the Thermodynamic Properties of Glycine and l-Alanine in Aqueous Solutions at Different Temperatures

Recently, ionic liquids have been combined with active pharmaceutical ingredients (APIs), and a third generation of ILs has emerged (API-ILs). The effect of a novel ionic liquid containing the ibuprofenate anion as an active pharmaceutical ingredient ionic liquid (API-IL) on the thermodynamic properties of two amino acids, glycine and l-alanine, have been studied. The densities, speeds of sound, viscosities and refractive indices of glycine and l-alanine in water and in aqueous solutions of an API-IL, 1-butyl-3-methylimidazolium ibuprofenate ([BMIM][Ibu]), have been determined at temperatures 288.15-318.15 K. The measured data have been used to calculate the standard partial molar volume Vφ0, partial molar volume of transfer ΔtrVφ0, Hepler's constant (?2Vφ0/?T2) p, apparent molar isentropic compressibility κφ, molar refraction R D, viscosity B coefficient (B) and hydration number parameters n H. All of these parameters are discussed in terms of the competitive interactions occurring between amino acids-[BMIM][Ibu] and amino acids-water.

Improved transdermal permeability of ibuprofen by ionic liquid technology: Correlation between counterion structure and the physicochemical and biological properties

The aim of this study was to explore the feasibility of transdermal delivery of ibuprofen using ionic liquid technology. Ibuprofen, a non-steroidal anti-inflammatory drug, was transformed into nine ionic liquids using aromatic, tetraalkylammonium and tetr

A simple halide-to-anion exchange method for heteroaromatic salts and ionic liquids

A broad and simple method permitted halide ions in quaternary heteroaromatic and ammonium salts to be exchanged for a variety of anions using an anion exchange resin (A- form) in non-aqueous media. The anion loading of the AER (OH- form) was examined using two different anion sources, acids or ammonium salts, and changing the polarity of the solvents. The AER (A- form) method in organic solvents was then applied to several quaternary heteroaromatic salts and ILs, and the anion exchange proceeded in excellent to quantitative yields, concomitantly removing halide impurities. Relying on the hydrophobicity of the targeted ion pair for the counteranion swap, organic solvents with variable polarity were used, such as CH3OH, CH3CN and the dipolar nonhydroxylic solvent mixture CH3CN:CH2Cl 2 (3:7) and the anion exchange was equally successful with both lipophilic cations and anions.