128992-97-2Relevant academic research and scientific papers
Addition-Cyclization Reactions of Cinnamoyl Isothiocyanate with Nitrogen and Oxygen Nucleophiles
Ahmed, A. F. Sayed,Aouf, N.,Assy, M. G.
, p. 2056 - 2061 (2007/10/03)
Bithiourea 2 obtained from isothiocyanate 1 and thiosemicarbazide was cyclized to yield triazolopyrimidine (5). Addition cyclization of dibenzylamine or N-methylaniline and compound 1 gave thiazines 7a,b. Refluxing of 1 and sodium ethoxide provided thiazine 8. Reaction of hydrazine and isothiocyanate 1 afforded triazole 12 that reacted with malononitrile or 1,3-cyclohexanedione to give triazolopyridine 14 and triazoloquinoline 16 respectively. The synthesis of triazolothiazine 19 is also described.
INTRAMOLECULAR CYCLIZATION OF O-ALKYL-N-(3-PHENYLPROPENOYL)THIOCARBAMATES CATALYZED BY BORON TRIFLUORIDE
Dzurilla, Milan,Kutschy, Peter,Koscik, Dusan,Toma, Stefan
, p. 710 - 717 (2007/10/02)
2-Alkoxy-6-phenyl-5,6-dihydro-4H-1,3-thiazin-4-ones, 6-phenyl-1,3-perhydrothiazine-2,4-dione and S-methyl N-(3-phenylpropenoyl)thiocarbamate are the products of intramolecular rearrangement of O-alkyl N-(3-phenylpropenoyl)thiocarbamates catalyzed by boron
