129-38-4 Usage
Chemical structure
1-chloro-8-nitroanthracene-9,10-dione is a nitro-substituted derivative of anthracenedione with a chlorine atom at position 1.
Molecular weight
Approximately 312.67 g/mol
Appearance
Yellow to orange crystalline solid
Solubility
Soluble in organic solvents such as acetone, ethanol, and dimethyl sulfoxide (DMSO)
Reactivity
Can undergo various reactions to produce other functionalized anthracene derivatives
Applications
a. Organic synthesis
b. Pharmaceutical industry
c. Materials industry
d. Dye or pigment in industrial applications
Safety precautions
Handle with caution due to potential toxicity and harmful effects if not used properly
Stability
Stable under normal conditions, but sensitive to heat, light, and moisture
Storage
Store in a cool, dry, and well-ventilated area, away from heat, light, and incompatible substances
Hazardous properties
Toxic, corrosive, and may cause irritation to skin, eyes, and respiratory system
Disposal
Dispose of in accordance with local, national, and international regulations for hazardous chemicals
Regulatory information
May be subject to restrictions or regulations depending on the country or region
Synonyms
1-Chloro-8-nitro-9,10-anthraquinone, 1-chloro-8-nitro-9,10-dihydroxyanthracene-2,3-dione
Chemical classification
Nitro-substituted anthracene derivative, halogenated aromatic compound
Check Digit Verification of cas no
The CAS Registry Mumber 129-38-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 129-38:
(5*1)+(4*2)+(3*9)+(2*3)+(1*8)=54
54 % 10 = 4
So 129-38-4 is a valid CAS Registry Number.
129-38-4Relevant academic research and scientific papers
Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives
Bu,Deady,Finlay,Baguley,Denny
, p. 2004 - 2014 (2007/10/03)
A series of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidines bearing cationic side chains were prepared from aminoanthraquinones. The perimidines were prepared from 1-aminoanthraquinone by initial condensation with urea or dimethylacetamide. A series of 2-, 4-, 8-, and 11-carboxy derivatives of the dibenzisoquinolines were prepared from aminoanthraquinonecarboxylic acids. The cationic derivatives were prepared from these via amide, amine, or methylene linkers to study the effects of side chain positioning on biological activity. Within the series of carboxamide-linked compounds, the order of increasing cytotoxicity was 8- 4- 2- 11-. The 2- and 4-carboxamides showed substantial growth delays against in vivo subcutaneous colon 38 tumors in mice, but the 11-carboxamide had curative activity in this refractory model and is being investigated further.
Preparation of chloroanthraquinones from nitroanthraquinones
-
, (2008/06/13)
The nitro group of an α-nitroanthraquinone is replaced by chlorine by reaction with an ionic chloride in a solvent in the presence of an acid or of a compound which eliminates an acid. The ionic chloride may be an alkali metal, alkaline earth metal, ammonium or quaternary ammonium chloride. A molten tertiary amine hydrochloride can function as the ionic chloride, the acid and the solvent. The process permits one or more nitro groups of a poly-α-nitroanthraquinone to be selectively replaced.
