129-40-8

Usage

Uses

Used in Dye Industry:
1-chloro-5-nitroanthraquinone is used as a dye intermediate for the production of various colored dyes, contributing to its significance in the dye industry.
Used in Textile Industry:
In the textile industry, 1-chloro-5-nitroanthraquinone is used as a colorant to impart color to fabrics, enhancing their visual appeal and variety.
Used in Food Industry:
1-chloro-5-nitroanthraquinone serves as a colorant in the food industry, providing a wide range of colors to food products, thereby improving their appearance and consumer attraction.
Used in Cosmetics Industry:
As a colorant in cosmetics, 1-chloro-5-nitroanthraquinone is utilized to add color to various cosmetic products, ensuring their aesthetic appeal and consumer preference.
Used in Pharmaceutical Industry:
1-chloro-5-nitroanthraquinone is used in the pharmaceutical industry for its potential antimicrobial and anticancer properties, indicating its importance in the development of new drugs and treatments.
Used in Organic Synthesis:
As a reagent in organic synthesis, 1-chloro-5-nitroanthraquinone is employed in the preparation of other anthraquinone derivatives, highlighting its role in chemical research and compound development.
It is important to handle 1-chloro-5-nitroanthraquinone with care due to its classification as a hazardous chemical, as it can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C14H6ClNO4/c15-9-5-1-3-7-11(9)13(17)8-4-2-6-10(16(19)20)12(8)14(7)18/h1-6H

Upstream product

• 82-50-8 5-nitroanthraquinone-1-sulfonic acid 
• 7647-01-0 hydrogenchloride 
• 7719-09-7 thionyl chloride 
• 93804-31-0 potassium 5-nitroanthraquinone-1-sulfonate 
• 128-56-3 anthraquinone-1-sulphonic acid sodium salt 
• 109-06-8 α-picoline 
• 126-33-0 sulfolane 
• 82-35-9 1.5-dinitroanthraquinone 
• 57875-61-3 dinitro-anthraquinone 
• 1594-46-3 1,2-dichloro-anthraquinone 
• 129-39-5 1,8-dinitroanthraquinone 
• 14401-91-3 picoline hydrochloride 
• 60274-89-7 C₁₄H₆NO₇S^(1-)*Na⁽¹⁺⁾ 

Downstream Products

• 117-11-3 1-amino-5-chloroanthracene-9,10-dione 
• 245064-92-0 1,4-dihydroxy-5-chloro-9,10-anthraquinone 
• 138452-26-3 7-Chloro-1-phenylnaphth<1,2,3-cd>indol-6(2H)one 
• 138452-25-2 2-Benzyl-7-chloro-1-phenylnaphth<1,2,3-cd>indol-6(2H)one 
• 138452-29-6 7-Benzylamino-1-phenylnaphth<1,2,3-cd>indol-6(2H)-one 
• 138452-36-5 8-Chloro-3,11b-dibenzyl-2-phenyl-3,11b-dihydroanthra<1,9-de>-1,3-oxazin-7(2H)-one 
• 90575-11-4 C₂₄H₁₉ClO₂S 

Relevant academic research and scientific papers

Dichroic dye, and liquid crystal composition and liquid crystal device using the same

The present invention provides one or more dichroic dyes which exhibit high solubility in liquid crystal and a high order parameter. The dichroic dyes each have a first substituent having at least one cis-cyclohexane ring and/or a second substituent having at least one trans-cyclohexane ring. The dichroic dye(s) may be provided as a mixture including at least a first dichroic dye having at least the first substituent and a second dichroic dye having at least the second substituent. The dichroic dye(s) may also be provided as a plurality of dichroic dyes, each of the molecules of which has at least the first substituent and the second substituent. The present invention also provides a liquid crystal composition and a liquid crystal element including the one or more dichroic dyes.

Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives

A series of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidines bearing cationic side chains were prepared from aminoanthraquinones. The perimidines were prepared from 1-aminoanthraquinone by initial condensation with urea or dimethylacetamide. A series of 2-, 4-, 8-, and 11-carboxy derivatives of the dibenzisoquinolines were prepared from aminoanthraquinonecarboxylic acids. The cationic derivatives were prepared from these via amide, amine, or methylene linkers to study the effects of side chain positioning on biological activity. Within the series of carboxamide-linked compounds, the order of increasing cytotoxicity was 8- 4- 2- 11-. The 2- and 4-carboxamides showed substantial growth delays against in vivo subcutaneous colon 38 tumors in mice, but the 11-carboxamide had curative activity in this refractory model and is being investigated further.

Synthesis of Naphthindol-6(2H)-one Derivatives and Their Fluorescence Properties

Highly fluorescent 1-phenylnaphthindol-6(2H)-one (3b) and its 7-chloro and 7-amino derivatives were synthesized by reaction of 1-aminoanthraquinone with benzyl chloride in KOH-DMSO system, followed by treatment with aluminium chloride.The compound 3b was easily N-alkylated with various alkyl halides in KOH-DMSO system.The fluorescence quantum yields (Φf) of naphthindol-6(2H)-one derivatives 3 were high (0.5-0.7), except for 7-amino derivatives which did not fluoresce.The Φf of 7-chloro derivative (3d) was strongly dependent on solvent: 0.37 in ethanol; 0.02 in acetonitrile; 0 in benzene.The compounds 3 were demonstrated to be efficient laser dyes for 500-550 nm region.

Preparation of chloroanthraquinones from nitroanthraquinones

The nitro group of an α-nitroanthraquinone is replaced by chlorine by reaction with an ionic chloride in a solvent in the presence of an acid or of a compound which eliminates an acid. The ionic chloride may be an alkali metal, alkaline earth metal, ammonium or quaternary ammonium chloride. A molten tertiary amine hydrochloride can function as the ionic chloride, the acid and the solvent. The process permits one or more nitro groups of a poly-α-nitroanthraquinone to be selectively replaced.