1290088-93-5Relevant articles and documents
Palladium catalyzed stereoselective synthesis of 3-(anilinoarylmethylene)- 2-oxindoles as Hesperadin analogoues
Bararjanian, Morteza,Hosseinzadeh, Saeedeh,Balalaie, Saeed,Bijanzadeh, Hamid Reza
, p. 2644 - 2650 (2011/04/24)
Potentially bioactive 3-(anilinoarylmethylene)-2-oxindoles as Hesperadin analogoues have been synthesized via a two-step procedure: (a) an Ugi-4MCR and (b) reaction of the Ugi adduct with aniline in the presence of a palladium catalyst via domino Heck/Buchwald reaction. In all cases, a single isomer with the Z-configuration was obtained in good to high yields. Crown Copyright